Minimal Residual Disease in Hematologic Disorders
Abstract In almost no other area of medical oncology has the introduction of new drugs, combinations of chemotherapeutic agents, and novel biologic treatments caused such dramatic responses as it has in the treatment of malignant hematologic disorders.
S, Faderl, R, Kurzrock, Z, Estrov
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Despite a significant evolution in treatment strategies for early breast cancer (EBC) patients, up to 30% of them experience recurrence due to occult micrometastasis.
Mara S. Serafini +5 more
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Accurate quantification of minimal residual disease at day 15, by real-time quantitative polymerase chain reaction identifies also patients with B-precursor acute lymphoblastic leukemia at high risk for relapse [PDF]
Válerie de Haas +4 more
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Supplementary Table 4 from Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma [PDF]
Janine Stutterheim +6 more
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Blinatumomab vs historic standard‐of‐care treatment for minimal residual disease in adults with B‐cell precursor acute lymphoblastic leukaemia [PDF]
Nicola Gökbuget +14 more
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Molecular monitoring and minimal residual disease in the management of chronic myelogenous leukemia [PDF]
Michael R. Savona
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Identifying leukemia‐associated immunophenotype‐based individualized minimal residual disease in acute myeloid leukemia and its prognostic significance [PDF]
Jing‐Ni Sui +7 more
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Targeting Minimal Residual Disease
Minimal residual disease (MRD) represents a significant challenge in the treatment of various cancers, acting as a precursor to relapse and therapeutic resistance. This review discusses the clinical background of MRD, exploring its role as a critical determinant in patient outcomes.
Yu-Ting Chou +2 more
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