Results 151 to 160 of about 656,371 (370)

There is nothing minimal about residual disease [PDF]

Blood, 2018
Can the detection of measurable residual disease (MRD) become the standard approach for acute lymphoblastic leukemia (ALL)? In this issue of Blood,Wood et al1 use a highly sensitive sequencing approach that is an improvement on conventional methods by both performance characteristics and potential for standardization.
openaire   +3 more sources

Forecasting Irreversible Disease via Progression Learning [PDF]

arXiv, 2020
Forecasting Parapapillary atrophy (PPA), i.e., a symptom related to most irreversible eye diseases, provides an alarm for implementing an intervention to slow down the disease progression at early stage. A key question for this forecast is: how to fully utilize the historical data (e.g., retinal image) up to the current stage for future disease ...
arxiv  

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

Spillover and crossover effects of exposure to work‐related aggression and adversities: A dyadic diary study

Aggressive Behavior, Volume 49, Issue 1, Page 85-95, January 2023., 2023
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann, Jürgen Glaser, Tobias Greitemeyer   +2 more
wiley   +1 more source

A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups

Haematologica, 2009
Background Minimal residual disease is an important independent prognostic factor in childhood acute lymphoblastic leukemia. The classical detection methods such as multiparameter flow cytometry and real-time quantitative polymerase chain reaction ...
Carlos A. Scrideli, Juliana G. Assumpção, Mônica A. Ganazza, Marcela Araújo, Silvia R. Toledo, Maria Lúcia M. Lee, Elisabete Delbuono, Antonio S. Petrilli, Rosane P. Queiróz, Andrea Biondi, Marcos B. Viana, José A. Yunes, Silvia R. Brandalise, Luiz G. Tone   +13 more
doaj   +1 more source

Treatment of Adult Patients with Relapsed/Refractory B-Cell Philadelphia-Negative Acute Lymphoblastic Leukemia [PDF]

, 2019
The majority of adult patients affected by B-cell acute lymphoblastic leukemia (B-ALL) will relapse after an initial response, while approximately 20% will display primary resistant disease. Patients suffering from relapsed/refractory B-ALL have a very
Lanza, Francesco, Maffini, Enrico, Saraceni, Francesco   +2 more
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez, Armeen Mahvash, James P. Long, Marnix G. E. H. Lam, S. Cheenu Kappadath   +4 more
wiley   +1 more source

Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis

Haematologica, 2011
Background Most minimal residual disease-directed treatment interventions in current treatment protocols for acute lymphoblastic leukemia are based on bone marrow testing, which is a consequence of previous studies showing the superiority of bone marrow ...
Jana Volejnikova, Ester Mejstrikova, Tatana Valova, Leona Reznickova, Ladislava Hodonska, Vladimir Mihal, Jaroslav Sterba, Yahia Jabali, Daniela Prochazkova, Bohumir Blazek, Jiri Hak, Zdenka Cerna, Ondrej Hrusak, Jan Stary, Jan Trka, Eva Fronkova   +15 more
doaj   +1 more source

Differentiated Thyroid Cancer with Extrathyroidal Extension: Prognosis and the Role of External Beam Radiotherapy [PDF]

, 2010
A study was performed to identify variables that affected cause-specific survival (CSS) and local relapse-free rate (LRFR) in patients with differentiated thyroid cancer (DTC) and extrathyroid extension (ETE) and to examine the role of external beam ...
Brierley, James D., Panzarella, Tony, Sia, Michael A., Tsang, Richard W.   +3 more
core   +3 more sources