Results 191 to 200 of about 656,371 (370)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

High‐sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma [PDF]

, 1999
Júlia Almeida, Alberto Órfão, Mauricio Ocqueteau, Gema Mateo, Mercedes Corral, Ma Delores Caballero, Joan Bladé, Ma Jesus Moro, José‐Ángel Hernández‐Rivas, Jesús F. San Miguel   +9 more
openalex   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Methods to detect minimal residual disease

HemaSphere, 2018
Torsten Haferlach
doaj   +1 more source

Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia [PDF]

, 1996
J Brisco, Elizabeth Hughes, S. H. Neoh, Pamela J. Sykes, Ken Bradstock, Arno Enno, Jeff Szer, Kieran McCaul, AA Morley   +8 more
openalex   +1 more source

Influence of adipose-derived mesenchymal stromal cells on osteosarcoma minimal residual disease [PDF]

, 2015
Includes bibliographical references.2015 Summer.Introduction: Mesenchymal stromal cells (MSCs) have been shown to improve bone integration and healing in several preclinical studies and have therapeutic potential in limb salvage following massive bone ...
Aanstoos-Ewen, Megan
core  

Paddy Disease Detection and Classification Using Computer Vision Techniques: A Mobile Application to Detect Paddy Disease [PDF]

arXiv
Plant diseases significantly impact our food supply, causing problems for farmers, economies reliant on agriculture, and global food security. Accurate and timely plant disease diagnosis is crucial for effective treatment and minimizing yield losses.
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The study of minimal residual disease in acute lymphoblastic leukaemia [PDF]

, 1995
C. Knechtli, Nick Goulden, Kenneth Langlands, Michael Potter   +3 more
openalex   +1 more source

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Science Translational Medicine, 2016
J. Tie, Yuxuan Wang, C. Tomasetti, Lu Li, S. Springer, Isaac Kinde, Natalie Silliman, M. Tacey, H. Wong, M. Christie, S. Kosmider, Iain J Skinner, R. Wong, M. Steel, B. Tran, J. Desai, I. Jones, A. Haydon, T. Hayes, T. Price, R. Strausberg, L. Diaz, N. Papadopoulos, K. Kinzler, B. Vogelstein, P. Gibbs   +25 more
semanticscholar   +1 more source