Results 231 to 240 of about 212,106 (307)

Transcriptome Analysis of Minimal Residual Disease in Subtypes of Pediatric B Cell Acute Lymphoblastic Leukemia

Clinical Medicine Insights: Oncology, 2015
Jitsuda Sitthi-amorn, Betty Herrington, Gail Megason, Jeanette Pullen, Catherine Gordon, Shirley Hogan, Tejaswi Koganti, Chindo Hicks   +7 more
doaj  

MRDadaptis: self-adaptive parameter configuration enhances minimal residual disease detection in heterogeneous ctDNA samples. [PDF]

Brief Bioinform
Wang T, Lai X, Wang S, Xue Z, Liu Y, Zhu X, Wang X, Chang Z, Shao Y, Zhang X, Wang J.   +10 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Analytical validation of a hybrid-approach combining tumor-informed and tumor-agnostic bespoke ctDNA panel assay for the sensitive detection of minimal residual disease. [PDF]

PLoS One
Heo S, Ham SK, Lee H, Han B, Roh H, Jeong S, Kim HP, Bang D, Song SH, Kim TY.   +9 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Clinical implications of ctDNA-based minimal residual disease detection in newly diagnosed peripheral T-cell lymphoma: a single-center cohort study. [PDF]

Cell Commun Signal
Liang JH, Hua W, Yin H, Li Y, Zhang XY, Liang JH, Zhu LQ, Gao R, Wang CX, Shao Y, Pan BH, Zhang XY, Wu JZ, Ou QX, Li JY, Shen HR, Wang L, Xu W.   +17 more
europepmc   +1 more source

16. Minimal Residual Disease

Annals of Oncology, 2002
openaire   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Impact of Minimal Residual Disease on Early Recurrence of Liver Metastatic Colorectal Cancer. [PDF]

Cancer Sci
Kawashima M, Yamada T, Miyasaka T, Kanaka S, Kuriyama S, Uehara K, Matsuda A, Ohta R, Sonoda H, Taniai N, Yoshida H.   +10 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source