Results 121 to 130 of about 6,143,115 (301)

Optimal control of Newton-type problems of minimal resistance [PDF]

, 2006
We address Newton-type problems of minimal resistance from an optimal control perspective. It is proven that for Newton-type problems the Pontryagin maximum principle is a necessary and sufficient condition.
Plakhov, A.Yu., Torres, D.F.M.
core   +1 more source

Mechanical and thermal responses of random triply periodic minimal surface structures

Materials & Design
This study investigates the mechanical and thermal responses of stochastic Triply Periodic Minimal Surface (TPMS) structures fabricated using the laser powder bed fusion process with Ti-6Al-4V.
Maytawee Maneein, Thanakit Yuthchaiming, Chutima Pankul, Atikom Sombatmai, Teerapong Poltue, Vikram Ahuja, Raj Das, Patcharapit Promoppatum   +7 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Validation of material-invariant mechanical models for triply periodic minimal surface structures

Results in Materials
Their dual functionality makes triply periodic minimal surface (TPMS) sheet networks an ideal candidate for permeable, load-bearing cellular structures. The present study investigates Gyroid and Primitive structures in quasi-static compression.
Henri Kammler, Jan Kube, Hendrik Traub, Christian Hühne   +3 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

How to make a minimal genome for synthetic minimal cell [PDF]

, 2010
As a key focus of synthetic biology, building a minimal artificial cell has given rise to many discussions. A synthetic minimal cell will provide an appropriate chassis to integrate functional synthetic parts, devices and systems with functions that ...
王晶, Zhang, Liu-yan, Chang, Su-hua, Wang, Jing   +3 more
core   +1 more source

Chamfer distance for non-linear registration of Triply Periodic Minimal Surface lattices

Additive Manufacturing Letters
We present a 3D image registration technique for non-linear deformation estimation in Additive Manufacturing processes. The methodology involves comparing X-ray Computed Tomography (XCT) data with Computer Aided Design (CAD) models for Triply Periodic ...
Michela Lapenna, Francesco Faglioni, Keerthana Chand, Bardia Hejazi, Rita Fioresi, Giovanni Bruno   +5 more
doaj   +1 more source

A Property of Minimal Surfaces [PDF]

Proceedings of the National Academy of Sciences, 1953
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source