Results 181 to 190 of about 6,750 (303)

The Ethics of Informed Consent for Data Registries: Moving Beyond Moral Minimalism to the High Ground. [PDF]

Bioethics
Chingarande GR.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

From simplicity to complexity: A path to innovation in science and art. [PDF]

Proc Natl Acad Sci U S A
Goldstein JL.
europepmc   +1 more source

Minimalism i Spel, en djupare förståelse för begränsningar

, 2019
Spel som Journey (Thatgamecompany, 2012) och ICO (Team Ico, 2001) har betonats som minimalistiska spel och har lyckats skapa en känsla av minimalism. Samtidigt motsäger dem vad Towards Minimalist Game Design (Nealen & Saltsman & Boxerman, 2011 ...
Albrecht, Elias, Gullbo, Lucas
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Chinese version of the employee digital disconnection scale: development and validation. [PDF]

Front Public Health
Jin C, Li Y, Wang Q, Zhang N.
europepmc   +1 more source

"Natural relations" : a note on X'-structure

, 2013
With the rise of minimalism, many concepts related to the geometrical relations of phrase structure held fast to in earlier approaches have been reconsidered.
Grohmann, Kleanthes K.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

"Lying flat" in the fast lane: how first-tier Chinese university students retreat from hard-work. [PDF]

BMC Psychol
Qi Y, Huang P.
europepmc   +1 more source