Results 71 to 80 of about 224,803 (301)

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

Arthritis Care &Research, EarlyView.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen, Guohao Zhu, Afton L. Hassett, Daniel Clauw, Susan L. Murphy   +4 more
wiley   +1 more source

Modes and models in disorders of consciousness science [PDF]

, 2012
The clinical assessment of non-communicative brain damaged patients is extremely difficult and there is a need for paraclinical diagnostic markers of the level of consciousness.
Boly, Mélanie, Seth, Anil K
core   +1 more source

Subjectivity: A Case of Biological Individuation and an Adaptive Response to Informational Overflow [PDF]

, 2016
The article presents a perspective on the scientific explanation of the subjectivity of conscious experience. It proposes plausible answers for two empirically valid questions: the ‘how’ question concerning the developmental mechanisms of subjectivity ...
Jonkisz, Jakub
core   +3 more sources

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Children in Vegetative State and Minimally Conscious State: Patients’ Condition and Caregivers’ Burden

The Scientific World Journal, 2012
Caring for children in vegetative state (VS) or minimally conscious state (MCS) challenges parents and impacts on their well-being. This study aims to evaluate caregivers’ health condition, coping, anxiety and depression levels, and how these issues ...
A. M. Giovannetti, M. Pagani, D. Sattin, V. Covelli, A. Raggi, S. Strazzer, E. Castelli, A. Trabacca, A. Martinuzzi, M. Leonardi   +9 more
doaj   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

Sleep in disorders of consciousness: behavioral and polysomnographic recording

BMC Medicine, 2020
Background Sleep-wakefulness cycles are an essential diagnostic criterion for disorders of consciousness (DOC), differentiating prolonged DOC from coma.
Isabella Mertel, Yuri G. Pavlov, Christine Barner, Friedemann Müller, Susanne Diekelmann, Boris Kotchoubey   +5 more
doaj   +1 more source

General anesthesia reduces complexity and temporal asymmetry of the informational structures derived from neural recordings in Drosophila

, 2020
We apply techniques from the field of computational mechanics to evaluate the statistical complexity of neural recording data from fruit flies. First, we connect statistical complexity to the flies' level of conscious arousal, which is manipulated by ...
Cohen, Dror, Leung, Angus, Modi, Kavan, Muñoz, Roberto N., Pollock, Felix A., Tsuchiya, Naotsugu, van Swinderen, Bruno, Zecevik, Aidan   +7 more
core   +1 more source

Assessment and detection of pain in noncommunicative severely brain-injured patients. [PDF]

, 2010
peer reviewedDetecting pain in severely brain-injured patients recovering from coma represents a real challenge. Patients with disorders of consciousness are unable to consistently or reliably communicate their feelings and potential perception of pain ...
Ambuel, Buttner, Camille Chatelle, Caroline Schnakers, Chatelle, Fuchs-Lacelle, Haenggi, Hummel, Lawrence, Lefebre-Chapiro, Marie De Val, Merkel, Morello, Olivia Gosseries, Pudas-Tahka, Schnakers, Sessler, Steve Majerus, Steven Laureys, Stevens, Stevens, Warden, Wijdicks, Zwakhalen   +23 more
core   +1 more source

Cognitive impairment, clinical symptoms and functional disability in patients emerging from the minimally conscious state

NeuroRehabilitation (Reading, MA), 2020
BACKGROUND: Although emergence from the minimally conscious state (eMCS) is associated with symptoms including disorientation, memory and attention impairment, restlessness, and significant functional disability, the neurobehavioral profile of eMCS has ...
Yelena G. Bodien, G. Martens, Joseph Ostrow, Kristen E. Sheau, J. Giacino   +4 more
semanticscholar   +1 more source