Results 51 to 60 of about 8,249 (202)

Minimally Invasive Optical Biopsy for Oximetry [PDF]

open access: yes, 2017
The study of localised oxygen saturation in blood vessels can shed light on the etiology and progression of many diseases with which hypoxia is associated.
Brewer, James M.   +2 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Microfabricated Implantable Parylene-Based Wireless Passive Intraocular Pressure Sensors [PDF]

open access: yes, 2008
This paper presents an implantable parylene-based wireless pressure sensor for biomedical pressure sensing applications specifically designed for continuous intraocular pressure (IOP) monitoring in glaucoma patients. It has an electrical LC tank resonant
Chen, Po-Jui   +4 more
core   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

Role of minimally invasive glaucoma procedures increasing the outflow of aqueous humor through the conventional pathway in advanced treatment of glaucoma

open access: yesKlinika Oczna
The objective of glaucoma surgery is to prevent the progression of the disease. In practice, surgical treatment of glaucoma is typically undertaken when pharmacotherapy is ineffective, poorly tolerated, contraindicated, or improperly used by the patient.
Łukasz Kempys, Ewa Mrukwa-Kominek
doaj   +1 more source

Personalized Medicine in Ocular Fibrosis: Myth or Future Biomarkers [PDF]

open access: yes, 2016
SIGNIFICANCE: Fibrosis-related events play a part in the pathogenesis or failure of treatment of virtually all the blinding diseases around the world, and also account for over 40% of all deaths.
Khaw, PT, Yu-Wai-Man, C
core   +1 more source

Effect of Budesonide Nasal Irrigation in Patients With Chronic Rhinosinusitis With Nasal Polyps Without Prior Sinus Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana   +5 more
wiley   +1 more source

Minimally Invasive Glaucoma Surgery [PDF]

open access: yes, 2010
Elie Dahan   +6 more
  +5 more sources

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