Results 171 to 180 of about 6,008 (306)

Minimum variance unbiased estimation and loss of information

Minimum variance unbiased estimation and loss of information
2011 【要旨】
openaire  

High‐Resolution Multiplexed Sequencing of Single‐Cell Full‐length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion

Advanced Science, EarlyView.
CBTi‐seq is reported, leveraging Tn5 transposase‐mediated molecular assembly of combinatorial barcodes and UMIs for high‐resolution multiplexed sequencing of the full‐length transcriptome in single cells. This approach achieves molecular resolution by end‐to‐end sequencing, enabling reconstruction of splice variants and accurate quantification of ...
Liyong He, Kaitong Dang, Qian Sun, Wenjia Wang, Wenbo Li, Wenyi Zhang, Kaiqiang Ye, Handong Wang, Zhengyue Li, Yan Guo, Zheng Li, Chencheng Yao, Peng Li, Yan Huang, Xiangwei Zhao   +14 more
wiley   +1 more source

A two-stage randomized response technique for simultaneous estimation of sensitivity and truthfulness. [PDF]

Sci Rep
Khan SA, Alomair MA, Qureshi M, Alomair AM.   +3 more
europepmc   +1 more source

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

Estimation of the distribution function of a finite population utilizing auxiliary information in the context of non-response within complex survey sampling. [PDF]

PLoS One
Abbas M, Ahmed Shehzad M, Khurram H, Rabia M.   +3 more
europepmc   +1 more source

The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid

Advanced Science, EarlyView.
Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek‐key motif in which extensive hydrogen bonding and packing interactions formed by residues in conserved imperfect repeats stabilize a β‐solenoid core.
Samuel Peña‐Díaz, Yanting Jiang, Zhefei Zhang, Anders Daugberg, Pedro Ferreira, Marcos López Hernández, Chandrika Mittal, Maria Joao Ramos, Jan Skov Pedersen, Morten Kam Dahl Dueholm, Cao Qin, Huabing Wang, Daniel E. Otzen   +12 more
wiley   +1 more source

Lasso Monte Carlo, a variation on multi fidelity methods for high-dimensional uncertainty quantification. [PDF]

J Appl Stat
Albà A, Boiger R, Rochman D, Adelmann A.   +3 more
europepmc   +1 more source

Uniformly Minimum Variance Unbiased Estimators (UMVUE) Not Attaining Cramer-Rao Lower Bounds

Subhash Bagui, K. L. Mehra
openalex   +2 more sources

Quantitative Assessment of Randomized DNA Base Sequences Using Multi‐Model Physical Analysis for High‐Fidelity Data Storage

Advanced Science, EarlyView.
This study quantitatively evaluates randomized DNA sequence design for digital data storage using three physics‐based models. By applying encoding schemes with strict homopolymer constraints, the framework improves base randomness, GC balance, and error resilience. Experimental validation via PCR and Sanger sequencing confirms 95–98% decoding accuracy,
Seongjun Seo, Thi Hong Nhung Vu, Anshula Tandon, Suyoun Park, Thi Bich Ngoc Nguyen, Shinsuke Kawai, Sung Ha Park   +6 more
wiley   +1 more source

Economic and demographic influences on health expenditures: robust approaches for income and aging effects. [PDF]

Health Econ Rev
Boz C, Kurnaz FS.
europepmc   +1 more source