Results 191 to 200 of about 74,320 (358)

Near‐Freezing‐Temperature Golgi Neuronal Staining for X‐ray Imaging of Human Brain

open access: yesAdvanced Science, EarlyView.
A near‐freezing temperature staining strategy, combined with a mercury chloride‐based method, effectively preserves delicate neuronal structures in post‐mortem frozen human brain tissues by minimizing autolysis. This approach enables uniform labeling across centimeter‐scale slices and, when integrated with synchrotron‐based X‐ray microscopy, achieves ...
Feng Zhou   +12 more
wiley   +1 more source

Adaptive Machine Learning for Electronic Nose‐Based Forensic VOC Classification

open access: yesAdvanced Science, EarlyView.
A 32‐element electronic nose enhanced with machine learning demonstrates exceptional accuracy in differentiating between living and deceased individuals (98.1%), discriminating human and animal specimens (97.2%), and estimating postmortem intervals.
Ivan Shtepliuk   +3 more
wiley   +1 more source

Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial Infection

open access: yesAdvanced Science, EarlyView.
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai   +14 more
wiley   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

open access: yesAdvanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen   +17 more
wiley   +1 more source

On Minimum Variance Unbiased Estimation of Clock Offset in a Two-Way Message Exchange Mechanism

open access: yesIEEE Transactions on Information Theory, 2010
Q. Chaudhari, E. Serpedin, K. Qaraqe
semanticscholar   +1 more source

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

open access: yesAdvanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser   +20 more
wiley   +1 more source

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