Results 251 to 260 of about 74,320 (358)

The interplay among space, environment, and gene flow drives genetic differentiation in endemic Baja California Agave sobria subspecies

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Research on neutral and adaptive processes that lead to the divergence of species and populations is a crucial component in evolutionary and conservation genetics. Agave sobria is an endemic group of subspecies scattered on canyons along a latitudinal gradient and distinct environments of the Baja California Peninsula, Mexico.
Anastasia Klimova   +4 more
wiley   +1 more source

Controlling Assembly of Hybrid DNA Nanostructures into Higher‐Order Structures via Hydrophobicity

open access: yesAngewandte Chemie, EarlyView.
We harness hydrophobic interactions, fundamental in biology yet underutilized in DNA nanotechnology, to build a design framework for hierarchical DNA assemblies. By conjugating small hydrophobic molecules to DNA motifs, we controlled the formation of higher‐order structures, moving beyond traditional Watson–Crick pairing.
Minu Saji   +4 more
wiley   +1 more source

Small Molecule‐Induced Alterations of Protein Polyubiquitination Revealed by Mass‐Spectrometric Ubiquitome Analysis

open access: yesAngewandte Chemie, EarlyView.
To monitor small molecule‐induced changes in protein polyubiquitination in an unbiased manner, we employ enrichment through tandem ubiquitin binding entities coupled to LC‐MS/MS analysis (TUBE‐MS). By applying the workflow to PROTAC, p97‐ and deubiquitinase‐inhibitor treatment of cells, we demonstrate its broad applicability and reveal the induction of
Siska Führer   +6 more
wiley   +1 more source

On the Error Metrics Used for Direction of Arrival Estimation. [PDF]

open access: yesSensors (Basel)
Hannan MA   +3 more
europepmc   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Procedures to combine estimators of greenhouse gases emission factors. [PDF]

open access: yesCarbon Balance Manag
Marujo EC, Rodrigues GG, Covatti AA.
europepmc   +1 more source

Cross-prediction-powered inference. [PDF]

open access: yesProc Natl Acad Sci U S A
Zrnic T, Candès EJ.
europepmc   +1 more source

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