Results 31 to 40 of about 7,253 (254)
With the increase in engine power density, the temperature and stress carried by the cylinder head during operation also increase. The thermal engine fatigue life prediction of the cylinder head needs to consider accurate and reasonable creep ...
Guoxi Jing +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
It is well-known that the creep equation obtained by the modified θ projection [2] describes well from the primary creep region to the tertiary creep region.
Hideo Hiraguchi
doaj +1 more source
High Temperature Behavior of Al-7Si-0.4Mg Alloy with Er and Zr Additions
In recent years, many efforts have been devoted to the development of innovative Al-based casting alloys with improved high temperature strength. Research is often oriented to the investigation of the effects of minor element additions to widely diffused
Elisabetta Gariboldi +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
In this work, we have investigated the influence of RE content on the tensile property, creep resistance, and microstructures of a die-cast Mg–9Al-0.3Ca-0.2Mn (wt. %).
Deping Zhang +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Creep data of Hastelloy X fabricated by laser powder bed fusion
The creep behavior of Hastelloy X fabricated by laser powder bed fusion was investigated, focusing on the testing temperatures of 700°C, 800°C, 900°C and 1000°C.
Kota Sawada +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

