Wild-type MIC distribution and evaluation of epidemiological cut-offs of second-line TB-drugs in susceptible and MDR-TB clinical isolates from Chennai, India. [PDF]
Dusthackeer A +7 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Bioelectrical Impedance Analysis in the Diagnosis of Sarcopenia in Oncological Patients: The Sarco-Detect Study. [PDF]
Jochem L +7 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Influence of Cutting-Edge Micro-Geometry on Material Separation and Minimum Cutting Thickness in the Turning of 304 Stainless Steel. [PDF]
Zou Z, Xin Y, Ma C.
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Sub-mV tunable photonic p-bits for probabilistic computing. [PDF]
Seo J +7 more
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
250 magnetic tunnel junctions-based probabilistic Ising machine. [PDF]
Yang S +6 more
europepmc +1 more source
Sparse graphs with an independent or foresty minimum vertex cut
A connected graph is called fragile if it contains an independent vertex cut. In 2002 Chen and Yu proved that every connected graph of order $n$ and size at most $2n-4$ is fragile, and in 2013 Le and Pfender characterized the non-fragile graphs of order $
Zhan, Xingzhi, Tang, Yurui, Cheng, Kun
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