Results 131 to 140 of about 7,149,925 (323)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Iterative min-sum decoding of tail-biting codes [PDF]
By invoking a form of the Perron-Frobenius theorem for the “min-sum” semi-ring, we obtain a union bound on the performance of iterative decoding of tail-biting codes.
Aji, Srinivas +3 more
core +2 more sources
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
The authors study the corn crop residue management system for 16 provinces in northern Thailand encompassing 127 agricultural cooperatives (co-ops), 974 corn fields and 274 customers.
Phonin Sirilak, Likasiri Chulin
doaj +1 more source
Insights into the binding and covalent inhibition mechanism of PF-07321332 to SARS-CoV-2 Mpro. [PDF]
Ngo ST, Nguyen TH, Tung NT, Mai BK.
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
FDR Adjustment for Achieving Desired Minimum Distance of Marine ESIM from the Shore
Determining and observing the minimum allowable distance of the marine earth station in motion (M-ESIM) from the shore prevents its destructive interference on the co-frequency shore fixed station.
Roghayeh Doost +3 more
doaj

