Results 221 to 230 of about 708,204 (381)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Antibiotic Susceptibility and Minimum Inhibitory Concentration for Stenotrophomonas maltophilia Ocular Infections. [PDF]

open access: yesAntibiotics (Basel), 2022
Ho MM   +7 more
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Efecto bacteriostático y/o bactericida del xilitol sobre cultivos de Listeria monocytogenes

open access: yesArchivos Latinoamericanos de Nutrición
Listeria monocytogenes ha sido considerado como un patógeno emergente causante de enfermedades alimentarias. En la búsqueda de una vía alterna biocontroladora de su propagación, se propone al xilitol como posible agente bacteriostático y/o bactericida ...
Alba Rosa Morón de Salim   +1 more
doaj  

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

open access: yesFEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy