Advanced Science, EarlyView.This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang +16 more
wiley +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Helical Milling of CFRP/Ti6Al4V Stacks Using Nano Fluid Based Minimum Quantity Lubrication (NF-MQL): Investigations on Process Performance and Hole Integrity. [PDF]
Materials (Basel), 2023 Mughal K +4 more
europepmc +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Optimisation on the Performance of Bubble-Bursting Atomisation for Minimum Quantity Lubrication with Vegetable Oil Using Computational Fluid Dynamics Simulation. [PDF]
Materials (Basel), 2022 Yap PH, Ghani JA, Wan Mahmood WMF.
europepmc +1 more source
Thermally Processable, Transparent, Mechanically Tunable and Robust Bioplastics From Wastepaper
Advanced Science, EarlyView.Unlike conventional inefficient or low‐value wastepaper recycling, a directional transformation strategy is employed to convert whole wastepaper into intact bioplastics with tunable mechanical properties in our work. These bioplastics can be processed into flexible bags or rigid containers and exhibit high transparency, water resistance, repairability,
Zhezhe Zhou +10 more
wiley +1 more source
Minimum Quantity Lubrication (MQL) Supply through Internal Cooling Channels in Drilling Processes
Journal of Manufacturing and Materials ProcessingMinimum quantity lubrication (MQL) technologies possess great potential for improving the sustainability of manufacturing processes, which can reduce the absolute quantity of metalworking fluid (MWF) and also enable near-dry chips that are easier to ...
Lukas Schumski +6 more
doaj +1 more source
The Influence of the Depth of Grinding on the Condition of the Surface Layer of 20MnCr5 Steel Ground with the Minimum Quantity Lubrication (MQL) Method. [PDF]
Materials (Basel), 2022 Stachurski W +3 more
europepmc +1 more source
Advanced Science, EarlyView.Fully programmable, in‐process 3D magnetization integrated with multi‐material printing enables soft magnetic systems with precise actuation and sensing. Discrete and continuous magnetization profiles drive bending, morphing, and locomotion, demonstrated through strain‐sensing elements, dragonfly‐inspired wings, octopus‐like tentacles, and a serpentine
Phillip Glass +5 more
wiley +1 more source
Comparison of Surface Morphology and Tool Wear in the Machining of Ti-6Al-4V Alloys with Uncoated and TiAlN Tools under Dry, Minimum Quantity Lubrication, Flood Cooling, and Low-Temperature Spray Jet Cooling Conditions. [PDF]
Micromachines (Basel), 2023 Zhao J +11 more
europepmc +1 more source