Results 51 to 60 of about 1,237,069 (236)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dryland maize yields and water use efficiency in response to tillage and nutrient management practices in China [PDF]

open access: yes, 2009
Rainfed crop production in northern China is constrained by low and variable rainfall. This study explored the effects of tillage and nutrient management practices on maize (Zea mays L.) yield and water use efficiency (WUE), at Shouyang Dryland Farming ...
Zhao, Q.   +5 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Potential Impacts of Soil Tillage System on Isoflavone Concentration of Soybean as Functional Food Ingredients

open access: yesLand, 2020
Soybean is an important natural source of isoflavones, but their concentration is likely to be influenced by external factors, such as climatic conditions and soil tillage systems.
Liliana Mureșan   +5 more
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

RESEARCH REGARDING THE INFLUENCE WEED CONTROL TREATMENTS ON PRODUCTION AND QUALITATIVE INDICATORS SOYBEAN CULTIVATED IN MINIMUM TILLAGE SYSTEM

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Agriculture, 2016
The use of herbicides abused, without a thorough knowledge can be dangerous for the environment through the introduction of toxic waste in agricultural ecosystems. It is necessary to reduce the doses used in relation to the use of conservative technology,
Cornel Chetan   +3 more
doaj   +1 more source

Minimum-tillage, mechanized sowing of pulses with two-wheel tractors [PDF]

open access: yes, 2010
Pulse crops in Bangladesh are mainly low-input rainfed crops with broadcast sowing. Since the 1990s, rotary tillage two-wheel tractors (2WT) have largely replaced animal draft for crop establishment.
Esdaile, R.J.   +9 more
core  

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

open access: yesAdvanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara   +8 more
wiley   +1 more source

The impact of different soil tillage on weed infestation of spring barley in conditions of dryer climatic areas Czech Republic

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2008
The impact of soil tillage on weeds in spring barley was observed on the field trial. The field trial was established in very warm and dry climatic region (experimental field station in Žabčice, Mendel University of Agriculture and Forestry Brno, Czech ...
Jan Winkler
doaj   +1 more source

Soil water use efficiency under integrated soil management practices in the drylands of Kenya

open access: yesHeliyon, 2023
Soil moisture scarcity and soil fertility decline in the drylands contribute to declining crop productivity. The possible synergistic effects of integrating soil & water conservation, and soil fertility management practices on soil moisture, and ...
O. Nathan Oduor   +5 more
doaj   +1 more source

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