Results 121 to 130 of about 2,827,443 (335)

Genetic divergence, traits association, path analysis and harvest index in pigeonpea (Cajanus Cajan L.)

open access: yesElectronic Journal of Plant Breeding, 2019
Twenty six genotypes of pigeonpea were evaluated for 13 agro-morphological characters. Statistical analysis was carried out for estimation of various parameters. The ICPL-87 being shortest genotypes possessed the minimum number of branches, minimum pod
Basudev Satapathy   +5 more
doaj   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Design and fabrication of a boron reinforced intertank skirt [PDF]

open access: yes
Analytical and experimental studies were performed to evaluate the structural efficiency of a boron reinforced shell, where the medium of reinforcement consists of hollow aluminum extrusions infiltrated with boron epoxy.
Henshaw, J., Pylypetz, P., Roy, P. A.
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Advanced technology for minimum weight pressure vessel system [PDF]

open access: yes
Bosses were made of fiber/resin composite materials to evaluate their potential in lightweight pressure vessels. An approximate 25% weight savings over the standard aluminum boss was achieved without boss failures during burst tests.
Hamstad, M. A.   +2 more
core   +1 more source

Minimum Weight Perfect Matching via Blossom Belief Propagation [PDF]

open access: yes, 2015
Max-product Belief Propagation (BP) is a popular message-passing algorithm for computing a Maximum-A-Posteriori (MAP) assignment over a distribution represented by a Graphical Model (GM).
Ahn, Sungsoo   +3 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Design optimization of a well-known geometry for minimum weight utilizing the Density-Shape-Element Removal method (D-S-ER) [PDF]

open access: yesE3S Web of Conferences
The development of topology optimization (TO) methods gives designers new capabilities. A variety of TO techniques have recently been used in special circumstances to expand the capabilities of generalist techniques on particular niche issues. To achieve
Teke Ibrahim T., Ertas Ahmet H.
doaj   +1 more source

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