Results 131 to 140 of about 2,902,197 (338)
Development of Michell minimum weight structures [PDF]
Mitchell strain criterion for minimum weight structures using mathematical ...
Ghista, D. N., Resnikoff, M. M.
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Influence of analysis and design models on minimum weight design [PDF]
The results of numerical experiments designed to illustrate how the minimum weight design, accuracy, and cost can be influenced by: (1) refinement of the finite element analysis model and associated load path problems, and (2) refinement of the design ...
Ramanathan, R. K. +3 more
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Spawning season and fecundity of Sepia pharaonis In Bushehr coastal waters (Persian Gulf)
Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2011 Fecundity rate and spawning season for cuttlefish (Sepia pharaonis), a commercially important species in Busheher coastal waters were studied from December 2007 to May 2008. We collected 142 specimens and after their sexuality were 18 males, 3 immatures,
R Khodadadi email ; M Yahyavi; R Ghorbani; M.J Shabani
doaj
Solving Large-Scale Minimum-Weight Triangulation Instances to Provable Optimality [PDF]
, 2018 Andreas Haas
openalex +1 more source
Nonexistence of some ternary linear codes with minimum weight -2 modulo 9
, 2021 Toshiharu Sawashima, Tatsuya Maruta
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An Extension of the Brouwer–Zimmermann Algorithm for Calculating the Minimum Weight of a Linear Code [PDF]
, 2021 Stefka Bouyuklieva, Iliya Bouyukliev
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source