Results 41 to 50 of about 792,002 (266)

Minimum Weight Euclidean $$(1+\varepsilon )$$-Spanners

open access: yes, 2022
Given a set $S$ of $n$ points in the plane and a parameter $\varepsilon>0$, a Euclidean $(1+\varepsilon)$-spanner is a geometric graph $G=(S,E)$ that contains, for all $p,q\in S$, a $pq$-path of weight at most $(1+\varepsilon)\|pq\|$. We show that the minimum weight of a Euclidean $(1+\varepsilon)$-spanner for $n$ points in the unit square $[0,1]^2$
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Algorithm of numerical optimization of steel structures on basis of minimum weight criterion

open access: yesMATEC Web of Conferences, 2018
The description of the algorithm of steel structures optimal design is described in the article. The calculation model is represented by flat and spatial rod elements. The problem of optimization is resolved with the help of mathematical programming. The
Dmitrieva Tatiana
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tracking shoreline change using minimum convolution of Gaussian weight and squared differences

open access: yesFrontiers in Marine Science
Detecting and responding appropriately to temporal changes in the shoreline is an important task for protecting coasts. Video monitoring has been utilized as a powerful tool for detecting shoreline changes. Existing shoreline-tracking methods include the
Hojun Yoo   +4 more
doaj   +1 more source

MODIFIED WEIGHT MATRIX USING PRIM’S ALGORITHM IN MINIMUM SPANNING TREE (MST) APROACH FOR GSTAR(1;1) MODEL

open access: yesBarekeng, 2023
The Generalized Space-Time Autoregressive (GSTAR) model is able to utilize modeling of both space and time simultaneously. The existence of a weight matrix is one of the aspects that established this model.
Nur'ainul Miftahul Huda   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Minimum Weight Design of Trusses Using Heuristic Rules

open access: yesEngineering Transactions, 1996
The minimum weight design of truss structures, composed of elements chosen from catalogues of available profiles, is presented in the paper. A controlled enumeration method is supplied with a knowledge module, containing the problem-oriented information,
M. Pyrz
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Optimization of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations

open access: yesScience and Engineering of Composite Materials, 2018
A genetic algorithm-based method is proposed to globally optimize the stacking sequence of multi-sandwich-panel composite structures for minimum weight with strength and buckling considerations.
Fan Hai-Tao, Wang Hai, Chen Xiu-Hua
doaj   +1 more source

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