Results 61 to 70 of about 2,827,443 (335)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Sparse Blossom: correcting a million errors per core second with minimum-weight matching [PDF]
QuantumIn this work, we introduce a fast implementation of the minimum-weight perfect matching (MWPM) decoder, the most widely used decoder for several important families of quantum error correcting codes, including surface codes.
Oscar Higgott, Craig Gidney
doaj +1 more source
Randomized Algorithms for the Loop Cutset Problem
, 2011 We show how to find a minimum weight loop cutset in a Bayesian network with high probability. Finding such a loop cutset is the first step in the method of conditioning for inference.
Bar-Yehuda, R., Becker, A., Geiger, D.
core +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Barekeng, 2023 The Generalized Space-Time Autoregressive (GSTAR) model is able to utilize modeling of both space and time simultaneously. The existence of a weight matrix is one of the aspects that established this model.
Nur'ainul Miftahul Huda +4 more
doaj +1 more source
Tree-Based Construction of LDPC Codes Having Good Pseudocodeword Weights [PDF]
, 2005 We present a tree-based construction of LDPC codes that have minimum pseudocodeword weight equal to or almost equal to the minimum distance, and perform well with iterative decoding.
Kelley, Christine +2 more
core +4 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Tracking shoreline change using minimum convolution of Gaussian weight and squared differences
Frontiers in Marine ScienceDetecting and responding appropriately to temporal changes in the shoreline is an important task for protecting coasts. Video monitoring has been utilized as a powerful tool for detecting shoreline changes. Existing shoreline-tracking methods include the
Hojun Yoo +4 more
doaj +1 more source