Results 71 to 80 of about 792,002 (266)

Approximating the minimum weight steiner triangulation [PDF]

open access: yesDiscrete & Computational Geometry, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effect of cultivars on tree growth, yield and quality attributes of apple on espalier architecture under high density planting system

open access: yesJournal of Horticultural Sciences, 2019
Annual extension growth (AEG), an indicator of tree vigor, was recorded maximum (145.63 cm) in Granny Smith and minimum (111.04cm) in Spartan, where as correlation matrix showed negative relation between trunk cross sectional area (TCSA) and AEG. Granny
K K Srivastava   +3 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Accuracy of Predicted Resection Weights in Breast Reduction Surgery

open access: yesPlastic and Reconstructive Surgery, Global Open, 2018
Background:. Many insurance carriers continue to deny coverage for reduction mammaplasty unless a minimum amount of resected breast tissue per breast is achieved during surgery.
Theodore A. Kung, MD   +4 more
doaj   +1 more source

Minimum distance and the minimum weight codewords of Schubert codes

open access: yesFinite Fields and Their Applications, 2018
26 pages; Slightly revised version; to appear in Finite Fields ...
Sudhir R. Ghorpade, Prasant Singh
openaire   +4 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Minimum weight design of vertically vibrating 3-D machine foundation coupled to layered half-space 1

open access: yesComputer Assisted Methods in Engineering and Science, 2023
Dynamic optimization problem for a machine rigid block foundation on an inhomogeneous soil is considered. The soil deposit under the base of block corresponds to a layer with linearly varying properties overlying a uniform half-space.
Zbigniew Sienkiewicz, Bogdan Wilczyński
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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