Results 31 to 40 of about 2,355,992 (290)

Social Indicators for Arctic Mining [PDF]

open access: yes, 2011
This paper reviews and assesses the state of the data to describe and monitor mining trends in the pan-Arctic. It constructs a mining index and discusses its value as a social impact indicator and discusses drivers of change in Arctic mining.
Crow, Andrew   +4 more
core  

The politics of the doorstep : female survival strategies and the legacy of the miners’ strike 1984–85. [PDF]

open access: yes, 2000
This paper considers the legacy of continuing activism of women in the North East of England who organized in support of the 1984-85 miners' strike.
Spence, J., Stephenson, C.
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A survey on utilization of data mining approaches for dermatological (skin) diseases prediction [PDF]

open access: yes, 2011
Due to recent technology advances, large volumes of medical data is obtained. These data contain valuable information. Therefore data mining techniques can be used to extract useful patterns.
Adibi, N   +4 more
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

South African mineral law: A historical overview of the State’s regulatory power regarding the exploitation of minerals

open access: yesContree, 2012
The Mineral and Petroleum Resources Development Act 28 of 2002 [MPRDA] acknowledges that the country’s mineral resources belong to the nation. The State is subsequently appointed as custodian of these resources.
Elmarie van der Schyff
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Book review: Mining and Quarrying in the Ancient Andes: Sociopolitical, Economic and Symbolic Dimensions

open access: yesJournal of Lithic Studies, 2016
The high Andes is one of the world’s great metallogenic provinces having produced and still providing very significant amounts of copper, silver, tin and historically, of course, gold.
Robert A. F. F.-X. Ixer
doaj   +1 more source

Mine Green Mining

open access: yesEnergy Procedia, 2012
AbstractWith the mine development and utilization, the mine environment problems and subordinate geology disaster phenomenon it causes have been revealed gradually, some also lead to serious results. Therefore, the balanced relation of “resources mining - environmental protection - mining area sustainable development” is a very important topic of ...
openaire   +1 more source

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