Results 101 to 110 of about 168,749 (297)

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Full scale data augmentation mining of power new energy eng-ineering based on multi-level grid of spatial information

Dianxin kexue
The current data of electric power new energy engineering presents complex characteristics of multi-source heterogeneity, spatiotemporal coupling, and spatial non stationarity, which make the boundaries of the full-scale data mining area fuzzy and lead ...
WANG Wei, CAI Si, YE Xinyang, LI Zan, LU Ting, DUAN Yuxiang   +5 more
doaj  

Mining robust in situ phosphorus-accumulating organisms via single-cell RACS-Culture for rational ecosystem engineering [PDF]

Jian Xu, Jing Xiaoyan, Huihui Pan, Yanhai Gong, Yishang Ren, Liyan Wang, Runzhi Mu, Pengcheng Sun, Zhidian Diao, Yu Meng, Liming Huang, Xixian Wang, Tianliang Zhao, Jia Zhang, Yuetong Ji, Bo Ma, Yushu Jing   +16 more
openalex   +1 more source

Structural Variation and 3D Genome‐Driven DNA/RNA Methylation Divergence Contributing to Cotton Fiber Domestication

Advanced Science, EarlyView.
These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao, Shangkun Jin, Haojie Jiang, Tianyu Pan, Zesheng Rui, Xiaowen Shi, Ting Zhao, Zhanfeng Si, Xueying Guan, Yan Hu, Tianzhen Zhang, Lei Fang   +11 more
wiley   +1 more source

Characteristics and Comprehensive Utilization Practices of Stripping Waste Rocks from Vanadium-Titanium Magnetite

Kuangchan zonghe liyong
This is an article in the field of mining engineering. The vanadium and titanium magnetite iron ore mining process generates a large amount of stripped waste rock, which is divided into three main categories: stripped soil material, stripped rock ...
Min LONG, Mingbin GONG, Yaohui YANG, Yanbo XU, Chao CHEN   +4 more
doaj   +1 more source

DIGITALIZATION IN MINING ENGINEERING [PDF]

Mining Equipment and Electromechanics, 2020
Anatoly P. Komissarov, Yuliya A. Lagunova, Rustem Sh. Nabiullin, Olga A. Lukashuk   +3 more
openaire   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Research Progress on the Effects of Reducing Agents and Dephosphorization Agents on Direct Reduction-Magnetic Separation of High Phosphorus Oolitic Hematite

Kuangchan zonghe liyong
This is an article in the field of mining engineering. The effects of reducing agent and dephosphorization agent on the direct reduction of high phosphorus oolitic hematite were reviewed.
Hongda XU, Tichang SUN, Shichao WU, Xiaoxiao LIAN, Wenli HAN, Zongyi DENG   +5 more
doaj   +1 more source

Research on High Voltage Transmission and Transfer Engineering and Environmental Protection of Electromagnetic Radiation Based on Large Data Mining Technology

, 2019
Jinyang Li, Dan Yang, Rui Li, Lei Yunkai, Yiming Tang, Hanyu Wang   +5 more
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source