Results 141 to 150 of about 842,121 (320)

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Female students in engineering Geology, Mining, and Petroleum Engineering Comparison

Rudarsko-geološko-naftni Zbornik, 1997
Engineering professions generally went last decades through process of feminization, but not equally. The article is focused on one of the most male dominant profession - mining, geology and petroleum engineering (MGPE). This study will examine the percentage of female students and graduates from mining college and their achievement on undergraduate ...
Lažnjak, Jasminka, Gaurina-Međimurec, Nediljka   +1 more
openaire   +4 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Study on the evaluation of workface wall stability based on cloud model

Scientific Reports
To address the uncertainty and fuzziness during conventional workface rib spalling prediction, a rating system of workface wall stability considering subjective experience factor, mechanical performance of coal mass, workface production condition, and ...
Xichen Zhao, Weiming Guan, Jiayi Sun, Meng Xie, Zhiyi Zhang, Yingyuan Wen, Hongchao Zhao   +6 more
doaj   +1 more source

Improve Data Mining and Knowledge Discovery Through the Use of MatLab [PDF]

Data mining is widely used to mine business, engineering, and scientific data. Data mining uses pattern based queries, searches, or other analyses of one or more electronic databases/datasets in order to discover or locate a predictive pattern or anomaly
Beil, Robert, Martin, Dawn (Elliott), Shaykhian, Gholam Ali   +2 more
core   +2 more sources

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Durable Thin‐Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis

Advanced Science, EarlyView.
Water electrolysis using porous transport electrodes with sputter‐deposited, ionomer‐free thin films of rutile IrO2 catalyst suppresses Ir dissolution by >10x over other forms of IrOx. The rutile IrO2 catalyst prepared by this readily scalable electrode synthesis method provides stable cell operation at 3 A cm−2 while using low Ir loading (0.4 mg Ir cm−
James L. Young, Diana E. Beltrán, Sarah J. Blair, Ricardo P. M. Duarte, Makenzie R. Parimuha, Haoran Yu, Lonneke van Eijk, Kimberly S. Reeves, Tomas Grejtak, Jorge Martinez, Bennett A. Chao, Jacob Wrubel, Melissa E. Kreider, Elisa M. Miller, Julia D. Lenef, Karen N. Heinselman, Svitlana Pylypenko, David A. Cullen, Guido Bender   +18 more
wiley   +1 more source

Enhancing Binding by Electron Transfer at Heterointerfaces of Biochar‐Modified Hydrogel to Improve Utilization Efficiency of Wastewater Recovered Nutrients

Advanced Science, EarlyView.
Enhancing the utilization efficiency of nutrients recovered from wastewater is achieved through hydrogel modification by biochar. The strategy improves nutrient binding to hydrogels via electron transfer at heterointerfaces, thereby reducing nutrient release rate.
Hao Hu, Juncong Zou, Chenglin Zhang, Peng Li, Junnan Li, Yen Wah Tong, Jun Li, Yiliang He   +7 more
wiley   +1 more source

Study on hydration mechanism and ratio optimization of slag powder modified high-water material

Scientific Reports
This study addresses the challenges of high costs, low residual strength, and underutilization of industrial waste in high-water filling materials. It explores the modification of these materials using high-activity slag powder. Key findings include: (1)
Xiang Ma, Chenyang Liu, Liwei Zhai, Shengrong Xie, Chaowen Wu, Jian Yang   +5 more
doaj   +1 more source