Results 71 to 80 of about 35,884 (264)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha   +4 more
wiley   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

open access: yesAdvanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen   +14 more
wiley   +1 more source

Experimental evaluation of acceleration waveform replication on electrohydraulic shaking tables

open access: yesInternational Journal of Advanced Robotic Systems, 2016
An electrohydraulic shaking table is an essential experimental facility in many industrial applications to real-time simulate actual vibration situations including structural vibration and earthquake.
Gang Shen   +5 more
doaj   +1 more source

Design of automatic coal mining control system

open access: yesGong-kuang zidonghua, 2016
For problem of low automation degree of current fully-mechanized coal mining face, a design scheme of automatic coal mining control system was proposed, and realization scheme of automatic coal mining control technology of the system was expounded.
GENG Zexin   +6 more
doaj   +1 more source

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

open access: yesAdvanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

Development of running status monitoring system for hydraulic support based on dual RS485 buses

open access: yesGong-kuang zidonghua, 2014
To solve problem of lacking remote monitoring function of running status in existing electro-hydraulic control system for hydraulic support, a running status monitoring system for hydraulic support based on dual RS485 buses was developed.
YANG Shihua   +5 more
doaj   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

open access: yesAdvanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

A Synergistic Mining Method Combining Sidewall Retaining and Open Stoping with Delayed Backfilling for Preventing Stope Back Collapse

open access: yesApplied Sciences
Many challenges are commonly encountered in the underground mining of steeply dipping thin-to-medium-thick orebodies associated with weak hanging wall rockmass, such as stope back collapse, high ore dilution, and poor stoping stability.
Jiayou Jing   +5 more
doaj   +1 more source

Structural Colors from Modulated Topological Defects in Molecular Smectic Liquid Crystals

open access: yesAdvanced Science, EarlyView.
Rather than using dyes and pigments, nature produces the colors of some butterflies and beetles through optical interference phenomena. This study describes an original biomimetic strategy exploiting the spontaneous formation of modulated linear defects in thin films of 8CB, a common molecular liquid crystal.
Camille N. Mahyaoui   +7 more
wiley   +1 more source

An operation optimization method of a fully mechanized coal mining face based on semi-physical virtual simulation

open access: yesInternational Journal of Coal Science & Technology, 2019
A mathematical hydraulic support self-tracking model for three-machine cooperative mining is proposed to address low efficiency and difficulties in strategy evaluation of a fully mechanized coal face.
Hengbo Shi   +4 more
doaj   +1 more source

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