Results 181 to 190 of about 5,475 (207)

Minisatellite mapping in manic depression

Journal of Psychiatric Research, 1987
Hypervariable regions of DNA exist at many discrete loci in the human genome. Variations in the length of specific classes of hypervariable DNA termed "minisatellite" sequences may be detected by hybridisation of radioactive probes composed of a common 10-15 base pair repeat or "core" sequence which is shared by each of the minisatellite loci.
S, Hodgkinson, H M, Gurling, R H, Marchbanks, M, McInnis, H, Petursson   +4 more
openaire   +2 more sources

Spontaneous and induced minisatellite instability

ELECTROPHORESIS, 1997
AbstractMinisatellites provide not only the basis for DNA fingerprinting and DNA profiling but also extremely informative systems for analysing processes of tandem repeat turnover in the human genome. Minisatellite instability appears to involve distinct mutation processes in somatic and germline cells; in the germline, mutation is frequently dominated
Jeffreys, AJ, Bois, P, Buard, J, Collick, A, Dubrova, Y, Hollies, CR, May, CA, Murray, J, Neil, DL, Neumann, R, Stead, JD, Tamaki, K, Yardley, J   +12 more
openaire   +3 more sources

Biological significance of minisatellites

ELECTROPHORESIS, 1995
AbstractMinisatellites are tandemly repeated, highly variable DNA sequences found in most higher eukaryotes. These contain a core sequence resembling the chi sequence of Escherichia coli, which is a binding site for recombination proteins. Based on this, a generalized function of minisatellites to provide binding sites for recombination proteins in ...
openaire   +2 more sources

Heteroduplex analysis of minisatellite variability

ELECTROPHORESIS, 2005
AbstractMinisatellites are tandem repeat arrays of middle size (5–100 bp) repeat units widely distributed in eukaryotic genomes. They have been related to several important features of human genome biology, including gene regulation, chromosomal fragile sites, and imprinting.
Paula, Barros, Miguel G, Blanco, Francisco, Boán, Jaime, Gómez-Márquez   +3 more
openaire   +2 more sources

Minisatellites of the Y Chromosome

1994
In recent years, the use of VNTR polymorphisms has became one of the most successful changes in the field of forensic medicine for personal identification and paternity testing. VNTR sequences have been identified on all human chromosomes and usually they map at or close to the telomers (1).
FATTORINI, PAOLO, FLORIAN, FIORELLA, VATTA M, COSSUTTA F, DE CRISTINI F, ALTAMURA B. M, GRAZIOSI G.   +6 more
openaire   +2 more sources

Minisatellite DNA fingerprints of salmonid fishes

Animal Genetics, 1990
Summary. The human minisatellite probes 33‐6 and 33‐15 cross‐hybridized to DNA digests of Atlantic salmon, brown trout and rainbow trout revealing complex multi‐banded patterns. These DNA fingerprints (in excess of 40 resolvable fragments in some cases) were highly polymorphic, individual specific and found to be stable, both somatically and in the ...
J B, Taggart, A, Ferguson
openaire   +2 more sources

A pseudoautosomal minisatellite in the pig

Mammalian Genome, 1994
72656
SIGNER, EN, GU, F, GUSTAVSSON, I, ANDERSSON, L, JEFFREYS, AJ   +4 more
openaire   +3 more sources

Minisatellite surge spurs downlink infrastructure

Science, 2017
Budding ground station networks capture deluge of CubeSat data.
openaire   +2 more sources

Hypervariable ‘minisatellite’ regions in human DNA

Nature, 1985
The human genome contains many dispersed tandem-repetitive 'minisatellite' regions detected via a shared 10-15-base pair 'core' sequence similar to the generalized recombination signal (chi) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite.
A J, Jeffreys, V, Wilson, S L, Thein
openaire   +2 more sources

Fragile Sites and Minisatellite Repeat Instability

Molecular Genetics and Metabolism, 2000
Oliva Handt, Grant R. Sutherland and Robert I. Richards.
Handt, O., Sutherland, G., Richards, R.
openaire   +3 more sources