Results 31 to 40 of about 5,475 (207)

LEPStr: A database for Mycobacterium leprae short tandem repeats

Informatics in Medicine Unlocked, 2020
Short tandem repeats are short arrays of nucleotide sequences, and they have vital roles in many biological processes, including modulation of transcription, enhancement of gene expression, adaptation to a particular environment, and link to autosomal ...
Partha Sarathi Mohanty, Dimple Saikia, Siddhant Kalra, Farah Naaz, Avi Kumar Bansal, Harpreet Singh Pawar, Keshar Kunja Mohanty, Sandeep Sharma, Manjula Singh, Shripad A. Patil   +9 more
doaj   +1 more source

Mutation at the Human D1S80 Minisatellite Locus

The Scientific World Journal, 2012
Little is known about the general biology of minisatellites. The purpose of this study is to examine repeat mutations from the D1S80 minisatellite locus by sequence analysis to elucidate the mutational process at this locus.
Kuppareddi Balamurugan, Martin L. Tracey, Uwe Heine, George C. Maha, George T. Duncan   +4 more
doaj   +1 more source

Non-Canonical G-quadruplexes cause the hCEB1 minisatellite instability in Saccharomyces cerevisiae

eLife, 2017
G-quadruplexes (G4) are polymorphic four-stranded structures formed by certain G-rich nucleic acids in vitro, but the sequence and structural features dictating their formation and function in vivo remains uncertain.
Aurèle Piazza, Xiaojie Cui, Michael Adrian, Frédéric Samazan, Brahim Heddi, Anh-Tuan Phan, Alain G Nicolas   +6 more
doaj   +1 more source

Interleukin-4 gene intron 3 VNTR polymorphism in adult acute myeloid leukemia

Egyptian Journal of Medical Human Genetics, 2022
Background The proliferation of acute myeloid leukemia (AML) blast into the bone marrow microenvironment is controlled by cytokines. Interleukin-4 (IL-4) has recently been discovered to suppress the development and persistence of AML cells selectively ...
Nesma A. Safwat, Marwa R. El Najjar, Alia M. Saeed, Haydi S. Mohamed   +3 more
doaj   +1 more source

Recombination hotspot activity of hypervariable minisatellite DNA requires minisatellite DNA binding proteins [PDF]

Somatic Cell and Molecular Genetics, 1998
Hypervariable minisatellite DNA repeats are found at tens of thousands of loci in the mammalian genome. These sequences stimulate homologous recombination in mammalian cells [Cell 60:95-103]. To test the hypothesis that protein-DNA interaction is required for hotspot function in vivo, we determined whether a second protein binding nearby could abolish ...
W P, Wahls, P D, Moore
openaire   +2 more sources

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Transferrin gene expression in Salmo sp.

Acta Agriculturae Slovenica, 2018
Salmonidae family combines freshwater and anadromous fish species. Duplicates of numerous genomic DNA loci are characteristic for this family, some as a consequence of tetraploidisation, and others as independent doubling of discrete DNA regions.
Anja ČIBEJ, Simona SUŠNIK BAJEC
doaj   +1 more source

Parental Age, Inbreeding and Incubation Method Influence Extremely Low Hatching Success in the Ex‐Situ Population of the Extinct in the Wild Sihek

Animal Conservation, EarlyView.
Reproductive success rates are a key parameter determining the recovery potential of ex‐situ managed threatened species, with high rates often being required to produce offspring for wild releases while ensuring ex situ population viability. Here, we quantify reproductive success rates in the Extinct in the Wild sihek (Guam kingfisher) and find ...
Matthew J. Mitchell, Ryan N. Felice, John G. Ewen, Gina M. Ferrie, Erica Royer, Suzanne Medina, Scott Newland, Amanda E. Trask   +7 more
wiley   +1 more source

Multi-locus genotypes of Enterocytozoon bieneusi in captive Asiatic black bears in southwestern China: High genetic diversity, broad host range, and zoonotic potential. [PDF]

PLoS ONE, 2017
Enterocytozoon bieneusi is an obligate eukaryotic intracellular parasite that infects a wide variety of vertebrate and invertebrate hosts. Although considerable research has been conducted on this organism, relatively little information is available on ...
Lei Deng, Wei Li, Zhijun Zhong, Chao Gong, Xuefeng Cao, Yuan Song, Wuyou Wang, Xiangming Huang, Xuehan Liu, Yanchun Hu, Hualin Fu, Min He, Ya Wang, Yue Zhang, Kongju Wu, Guangneng Peng   +15 more
doaj   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

Animal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez, Anthony J. Clemento, Juliette E. Linossier, Daniel E. Crocker, Daniel P. Costa, Colleen Reichmuth, John Carlos Garza   +6 more
wiley   +1 more source