Results 191 to 200 of about 66,582 (246)

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Nurses' relevance in a century of tuberculosis prevention actions in Brazil. [PDF]

Rev Bras Enferm
Johansen FDC, Evangelista MDSN, Bertolozzi MR, Maciel ELN.   +3 more
europepmc   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Sand fly (Diptera: Psychodidae: Phlebotominae) species composition in an area with a recent American Tegumentary Leishmaniasis outbreak in Minas Gerais, Brazil. [PDF]

J Med Entomol
Dias ES, Michalsky ÉM, Rocha MFD, Pereira NCL, Saraiva L, Lara-Silva FO, Silva RAE, Fortes-Dias CL.   +7 more
europepmc   +1 more source

Coupled Above‐ and Belowground Ecosystem Stability Worldwide

Advanced Science, EarlyView.
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng, Huiwen Li, Yiping Wu, Peter B. Reich, Nico Eisenhauer, Diego Abalos, Daniel Revillini, Shuguang Liu, Wende Yan, Ji Chen, Alexey Voinov, Zhifeng Yang, Ying‐Ping Wang, Fubo Zhao, Linjing Qiu, Jingfeng Xiao, Shantao An, Guopeng Liang, Manuel Delgado‐Baquerizo   +18 more
wiley   +1 more source

[Knowledge, practices, and human seroprevalence of brucellosis in the central dairy-producing area of Cochabamba, BoliviaConhecimentos, práticas e soroprevalência humana de brucelose na área central de produção de laticínios de Cochabamba, Bolívia]. [PDF]

Rev Panam Salud Publica
Yanez RM, Quitón R, Rojas E, Vargas T, Eid D, Letesson JJ, Rodríguez P.   +6 more
europepmc   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of TCE‐secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

[Lessons learned in the implementation of measles and rubella vaccination campaigns in the AmericasLições aprendidas com a implementação de campanhas de vacinação contra sarampo e rubéola na Região das Américas]. [PDF]

Rev Panam Salud Publica
Durón R, Pastor D, Whittembury Á, Rocha Queiroz Lemos D.   +3 more
europepmc   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

[Comprehensive approach to the interruption of the measles outbreak in Venezuela, 2017-2019: lessons learnedAbordagem integral para a interrupção do surto de sarampo na Venezuela, 2017-2019: lições aprendidas]. [PDF]

Rev Panam Salud Publica
Muro L, Castillo L, Rodríguez L, D'Angelo P, Porras N, García JM, Valderrama N, Rodriguez R, Villalobos N, Torres C, Villavicencio V.   +10 more
europepmc   +1 more source