Results 71 to 80 of about 1,316,852 (299)

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

Hybrid Organizations in Health Systems: The Corporatization of Malaysia’s National Heart Institute

open access: yesHealth Systems & Reform, 2020
Health system reforms across high- and middle-income countries often involve changes to public hospital governance. Corporatization is one such reform, in which public sector hospitals are granted greater functional independence while remaining publicly ...
Amrit Virk   +10 more
doaj   +1 more source

The Report of Rumeli Advisory Committee and Answer of Edirne Governor Salim Pasha

open access: yesYakın Dönem Türkiye Araştırmaları, 2020
After the Armistice of Mudros, the Government of Istanbul decided to send boards called “Advisory Committees” to both Anatolia and Thrace in order to prevent public order crimes, establish love and friendship among the communities within the country. The
Burçin Işım
doaj   +1 more source

\u27Ministering Confusion\u27: Rebellious Quaker Women (1650-1660)\u27

open access: yes, 2014
This paper assesses the position of women within the Quaker community, concentrating on their ministerial roles. Female prophets and preachers were visible during the first decade of Quakerism, and the early years prove fruitful for exploration of women ...
Gill, Catie
core  

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

The Role of Health Institutions in Training Healthcare Personnel for the Digital Transition: The International Training Program of the Order of Physicians and Dentists of Rome

open access: yesInternational Medical Education
Digital health, encompassing the use of digital technologies in healthcare, and telemedicine, facilitating healthcare delivery across long distances, have witnessed widespread applications across various healthcare domains.
Maria Chiara Gatto   +7 more
doaj   +1 more source

THE NEED FOR PUBLIC DEBT MANAGEMENT IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT WITHIN THE EUROPEAN UNION [PDF]

open access: yes
Public debt is created when the necessary resources for the socio-economic development of a state are greater than the opportunities that exist at that time.
Marcu Nicu, Meghisan Madalina Georgeta
core  

Anticipating climate change: knowledge use in participatory flood management in the river Meuse [PDF]

open access: yes, 2005
Given the latest knowledge on climate change, the Dutch government wants to anticipate the increased risk of flooding. For the river Meuse in The Netherlands, the design discharge is estimated to increase from 3800m3/s to 4600m3/s.
Krol, M.S., Reuber, J., Wesselink, A. J.
core   +4 more sources

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su   +10 more
wiley   +1 more source

Development of children's ecological awareness in "Płomyk" in the II Republic of Poland

open access: yesFides et Ratio, 2018
The purpose of this article is to explain how the children's ecological awareness was built in Poland in the period between the two world wars (1918-1939) on the example "Płomyk", a periodical, issued in Warsaw since 1917.
Edyta Wolter
doaj  

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