Results 71 to 80 of about 1,405,996 (300)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

What’s in My Backyard? Empowering Indigenous Voices on Firefly Creek at Blue’s Bottom

open access: yesOpen Rivers, 2019
All of us, regardless if we are Native or non-native, hold a specific location near and dear to our hearts. In this article, I focus on a place near and dear to my heart, exploring the history of my family’s cul-de-sac area known to my family, and much ...
Tianna M. Odegard
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Giving in Minnesota, 2009 Edition [PDF]

open access: yes, 2009
The Minnesota Council on Foundations has produced its Giving in Minnesota, 2009 Edition research report, the most comprehensive analysis of charitable giving in the state. The 2009 edition features Minnesota giving in 2007, the most recent year for which
Anne Graham, Juliana Tillema, Wendy Wehr
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Making The Most of the Governor's Water Summit

open access: yesOpen Rivers, 2016
When over 800 Minnesotans gather in a windowless basement on the first beautiful spring-like day, there must be a compelling reason. In this case the reason was water.
Alicia Uzarek
doaj   +1 more source

Giving in Minnesota, 2011 Edition [PDF]

open access: yes, 2011
The Minnesota Council on Foundations (MCF) has produced its Giving in Minnesota, 2011 Edition research report, the most comprehensive analysis of charitable giving in the state.
Anne Bauers, Anne Graham, Wendy Wehr
core  

Spruce Budworm Weight and Fecundity: Means, Frequency Distributions, and Correlations for Two Populations (Lepidoptera: Tortricidae) [PDF]

open access: yes, 2017
Pupal weights and fecundities of spruce budworm from Minnesota had different means, coefficients of variation, and frequency distributions than spruce budworm from New Hampshire.
Bauer, Leah S, Lorimer, Nancy
core   +3 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

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