Results 101 to 110 of about 53,842 (242)

Effects of Minocycline as a Neuroprotective Agent for Stroke on Mmp-9 Levels, Functional Outcome, and Mortality

Folia Medica Indonesiana
Highlights: 1. As minocycline plays an important role in stroke microglia activation and iron chelation, it is important to further analyze its effects on stroke treatment. 2.
Ayu Imamatun Nisa, Arlia Ayu Damayanti, Jeffri Nagasastra, Abdulloh Machin, Mohammad Fathul Qorib, Retnaningsih, Baarid Luqman Hamidi   +6 more
doaj   +1 more source

Minocycline through attenuation of oxidative stress and inflammatory response reduces the neuropathic pain in a rat model of chronic constriction injury [PDF]

, 2018
Objectives: Several lines of evidence showed that minocycline possesses antioxidant and anti-inflammatory properties. This study aimed to demonstrate the effects of minocycline in rats subjected to chronic constriction injury (CCI).
Aaliehpour, Asghar, Abbasnezhad, Amir, Abbaszadeh, Abolfazl, Amini-khoei, Hossein, Choghakhori, Razieh, Darabi, Saeideh, Hasanvand, Amin   +6 more
core   +2 more sources

Open-label add-on treatment trial of minocycline in fragile X syndrome [PDF]

, 2010
Background Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems.
Carlo Paribello, Leeping Tao, Anthony Folino, Elizabeth Berry-Kravis, Michael Tranfaglia, Iryna M Ethell, Douglas W Ethell   +6 more
core   +2 more sources

Management of Periodontal Abscesses and Endodontic‐Periodontal Lesions—A Systematic Review

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the management of periodontal abscesses and endodontic‐periodontal lesions (EPLs). Methods Seven focused questions addressed outcomes such as pocket depth (PD), bleeding on probing (BOP), tooth loss or ovoid elevation. The literature search covered three electronic databases and manual sources for intervention studies.
Henrik Dommisch, Daniela Hoedke, Marina Dourou, Elena Calciolari, David Herrera, Selena Toma   +5 more
wiley   +1 more source

Peripheral Inflammation Enhances Microglia Response and Nigral Dopaminergic Cell Death in an in vivo MPTP Model of Parkinson’s Disease [PDF]

, 2018
The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here, we have investigated the role of peripheral inflammation induced by systemic lipopolysaccharide (LPS) administration in the MPTP-based model of Parkinson’s ...
Carrillo Jiménez, Alejandro, García Domínguez, Irene, García Revilla, Juan, Martínez de Pablos, Rocío, Roca Ceballos, María Angustias, Santiago Pavón, Martiniano, Venero Recio, José Luis, Veselá, Karolina   +7 more
core   +3 more sources

Annual Research Review: Psychosis in children and adolescents: key updates from the past 2 decades on psychotic disorders, psychotic experiences, and psychosis risk

Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 460-476, April 2025.
Psychosis in children and adolescents has been studied on a spectrum from (common) psychotic experiences to (rare) early‐onset schizophrenia spectrum disorders. This research review looks at the state‐of‐the‐art for research across the psychosis spectrum, from evidence on psychotic experiences in community and clinical samples of children and ...
Ian Kelleher
wiley   +1 more source

Comparison of the Expression Changes after Botulinum Toxin Type A and Minocycline Administration in Lipopolysaccharide-Stimulated Rat Microglial and Astroglial Cultures

Frontiers in Cellular and Infection Microbiology, 2017
Botulinum neurotoxin type A (BoNT/A) and minocycline are potent drugs used in clinical therapies. The primary molecular mechanism of BoNT/A is the cleavage of SNARE proteins, which prevents cells from releasing neurotransmitters from vesicles, while the ...
Joanna Mika, Anna Piotrowska, Katarzyna Popiolek-Barczyk, Flaminia Pavone, Flaminia Pavone   +4 more
doaj   +1 more source

Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome. [PDF]

, 2020
BackgroundThe purpose of this study was to conduct a 20-week controlled trial of lovastatin (10 to 40 mg/day) in youth with fragile X syndrome (FXS) ages 10 to 17 years, combined with an open-label treatment of a parent-implemented language intervention (
Abbeduto, Leonard, Banasik, Amy, Bullard, Lauren, Hagerman, Randi, Kim, Kyoungmi, McDuffie, Andrea, Nguyen, Vivian, Potter, Laura A, Potter, Sarah Nelson, Tassone, Flora, Thurman, Angela John   +10 more
core  

Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast, Bassel H. Al Wattar, Marie Beylot Barry, Holger Brüggemann, Zrinka Bukvić Mokos, Dawn M. Caruana, Klaus Degitz, Clio Dessinioti, Brigitte Dréno, Rieke J. B. Driessen, Harald Gollnick, Merete Hædersdal, Alexander Katoulis, Severin Läuchli, Julien Lambert, Alison M. Layton, Giuseppe Micali, Falk R. Ochsendorf, Thozhukat Sathyapalan, Katarina Zak Stangeland, Simon Francis Thomsen, Daniel Töröcsik, Antonia Pennitz   +22 more
wiley   +1 more source

Efficacy and Safety of Quadruple Therapy With Semisynthetic Tetracycline for Helicobacter pylori Eradication: A Meta‐Analysis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background High antibiotic resistance and limited tetracycline accessibility severely restrict the clinical application of classic bismuth quadruple therapy (BQT), creating an urgent demand for alternative regimens. Methods A systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science up to June 3, 2025, for trials ...
Qi‐Qi Guo, Ju Zhang, Xiao‐Jing Zhu, Wei‐Yue Li, Dan‐Yang Zhao, Meng‐Qi Liang, Rong Yan, Yong‐Quan Shi   +7 more
wiley   +1 more source