Results 171 to 180 of about 1,713,707 (269)

Sialoblastoma of the Minor Salivary Glands: A Case Report. [PDF]

Case Rep Dent
Novelli G, Mangini G, Picozzi C, Di Bella C, Canzi G, Sozzi D.   +5 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Prevalence and biopsychosocial predictors of post-stroke fatigue in patients with minor strokes. [PDF]

J Rehabil Med
Kjeverud A, Andersson S, Lerdal A, Schanke AK, Østlie K.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tele-Electrocardiography and Mortality: Clinical Outcomes in Digital Electrocardiography Cohort-Data from Belo Horizonte, Brazil (CODE-BH). [PDF]

Glob Heart
Paixão GMM, Soares CPM, Rodrigues PG, Macfarlane PW, Ribeiro ALP.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Clinicopsychological stratification of recovery outcomes in cerebral aneurysm patients following cluster analysis. [PDF]

PNAS Nexus
Reder SR, Hardt J, Brockmann MA, Kantelhardt SR, Neulen A, Fassl V, Petrowski K, Fischbeck S.   +7 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Analysis of mental health outcomes in major versus minor upper extremity amputations: a retrospective national database study. [PDF]

Arch Orthop Trauma Surg
Nedder V, Wang J, Peek K.
europepmc   +1 more source