Results 201 to 210 of about 1,713,707 (269)

Structural basis for conserved and distinct antigen recognition by a lineage of malaria-protective antibodies. [PDF]

PLoS Pathog
Jain M, Cannac F, Agrawal S, Lee WH, Loeffler JR, Fernández-Quintero ML, González-Páez GE, Moskovitz R, Ward AB, Wilson IA.   +9 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Evidence for direct and sleep-moderated relationships between aquaporin-4 genetic variants and Alzheimer's disease phenotypes. [PDF]

Alzheimers Dement
Porter T, Armstrong AM, O'Brien EK, Doré V, Bourgeat P, Turner M, Maruff P, Rowe CC, Brown BM, Villemagne VL, Rainey-Smith SR, Laws SM, AIBL Research Group.   +12 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Modelling the Effects of Treatment Failure on the Minor Outbreak Duration for Carrier-Related Infectious Disease. [PDF]

Epidemiologia (Basel)
Voottipruex P, Patanarapeelert N, Patanarapeelert K.   +2 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Efficacy and safety of intravenous thrombolysis versus standard medical management for minor stroke: a systematic review and meta-analysis of RCTs. [PDF]

Front Neurol
Feng X, Tang Y, Wang B, Liu Z.
europepmc   +1 more source

B6 Donor Lungs Develop Chronic Lung Allograft Dysfunction-like Pathology Across Histocompatibility Mismatches in Murine Lung Transplantation. [PDF]

Transplant Direct
Kaiho T, Miyashita Y, Nagano T, Aillon RP, Yagi Y, Toyoda T, Budinger GRS, Bharat A, Suzuki H, Kurihara C.   +9 more
europepmc   +1 more source

Mechanical Compression Versus Vascular Closure Devices for Femoral Artery Haemostasis After Peripheral Endovascular Procedures: A Randomised Controlled Trial. [PDF]

J Clin Med
Shevchenko I, Lee BJ, Daudu D, Dodd J, Wong J, Oshin OA, Picazo-Pineda F, Al-Najjar M, Rhine TM, Bravo Ceballos C, Mwipatayi BP.   +10 more
europepmc   +1 more source