Results 121 to 130 of about 743,702 (309)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Sounding Out Municipal Housing in Vienna: Ethnographic Insights into Music and Sound in the Anton-Figl-Hof [PDF]

Musicologica Austriaca
Municipal housing in Vienna, called Wiener Gemeindebau, is gaining new significance in research and cultural work in the discourse on affordable housing in the city and the increasing heterogeneity of urban life.
Jasemin Anika Khaleli
doaj  

Increasing Public Interest in Online Education during the COVID-19 Pandemic in the United States: An Analysis of Google Trends Data

Journal of Education, Health and Sport
Objective: Current evidence suggests that the shift to online learning during the COVID-19 pandemic has profoundly impacted teaching and learning models.
Qinyi Tan, Ziqi Zhang, Luyan Teng
doaj   +1 more source

Employer hiring decisions and antidiscrimination policy [PDF]

Have federal antidiscrimination policies been effective in improving employment outcomes for minorities and females? If so, why have the relative wages and employment of blacks deteriorated in recent years?
H. J. Holzer
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Christian Roma Musicking in Hungary

Music & Minorities
In this article, we investigate Romani musicians and Romani religious musicking, a previously under-researched facet of Roma musicking. We detail the emergence of Romani religious music and its distinctive features, explore its evolution over the past ...
István Povedák, Kinga Povedák
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Sounding Traumatic Memory

Music & Minorities
This article examines the significance of music as a medium of memory in the broader context of Romani World War II remembrance and human rights activism of the last decade.
Martin Ringsmut
doaj   +1 more source

The excluded minors for the class of spike minors

Advances in Applied Mathematics
25 pages, 5 ...
Bastida, Sam, Brettell, Nick, Campbell, Rutger, Drummond, George, Hogan, Emma, Semple, Charles, Toft, Gerry   +6 more
openaire   +2 more sources