Results 111 to 120 of about 51,543 (217)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Does Character Strength Have an Influence on Children's Susceptibility to Technological Addiction? A Systematic Review. [PDF]

Healthcare (Basel)
Jimenez-Perianes A, Monfort-Vinuesa C, Saiz-Clar E, Egea-Romero MP, Rebate C, Rodriguez-Cañas M, Villarroel C, Rincon E.   +7 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Protein-truncating variants in APBA1 in minors with severe, early-onset obesity: implications for genetic testing. [PDF]

Mol Cell Pediatr
Lerner J, Moawia A, Zorn S, Kloker S, Klehr-Martinelli M, Winner K, Penfold D, Völkl TMK, Krausnick M, Siebert R, Wabitsch M.   +10 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Changes in health-related social needs and in depression and anxiety symptoms in Massachusetts low-income, community health center patients: an observational cohort study. [PDF]

Prev Med Rep
Wu Y, Cheng J, McCurley JL, Levy DE, Fung V, Clark CR, Thorndike AN.   +6 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Community as the key to socio-education: an analysis of challenges and practices in migratory contexts. [PDF]

Front Sociol
Santoro M, Iniesta Martínez A, Muñoz Sánchez P, Battista D, Santaniello D.   +4 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Protecting Minors From Medical Malpractice Act: Implications for Otolaryngology-Head & Neck Surgery. [PDF]

Laryngoscope
Sharma S, McKenna MK, Ongkasuwan J, Brenner MJ.   +3 more
europepmc   +1 more source