Results 71 to 80 of about 51,543 (217)
BMC Public HealthBackground Refugee minors are considered particularly vulnerable to negative health consequences from war, flight and resettlement. Offering health assessments after arrival in a host country could uncover unmet health needs and provide access to ...
Cecilie Dangmann +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Humanities & Social Sciences CommunicationsOver the past twenty years, brand communication strategies have evolved, particularly for younger audiences, with formats that blend advertising and entertainment content, often featuring influencers.
Erika Fernández-Gómez +2 more
doaj +1 more source
Public Libraries: Readers and Books. A Case Study on Services for Minor Readers in Guangdong, China
БиблиосфераThe purpose of this article is to clarify the evolving connotations of “readers” and “books” in public libraries, centers on a thriving segment of library patrons – minor readers. Taking the services for minors in Guangdong China as an example, the study
Song Ling
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Development of Minors Health Care System in Russian Federation
Вопросы современной педиатрииProtection of children and adolescents’ health is the priority of Russian state policy. An effective minors health care system is crucial for ensuring their well-being, preventing diseases, and forming healthy generation.
Anna V. Kazantseva +2 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Вестник Тамбовского университета. Серия: Гуманитарные наукиA retrospective analysis of the problem of prevention of criminal behavior of minors in Japan has been carried out. The relevance of the study lies in the fact that in many countries of the world and in Russia, in particular, the criminal behavior of ...
A. A. Kuleshov
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source