Results 1 to 10 of about 19,533 (291)

New Target for Minoxidil in the Treatment of Androgenetic Alopecia

Drug Design, Development and Therapy, 2023
Yuqing Shen,1 Yuqi Zhu,1 Li Zhang,1 Jiayi Sun,1 Bo Xie,2 Hongyan Zhang,2 Xiuzu Song2 1Department of Dermatology, Hangzhou Third People’s Hospital, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China; 2Department of Dermatology ...
Shen Y, Zhu Y, Zhang L, Sun J, Xie B, Zhang H, Song X   +6 more
doaj   +4 more sources

Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis [PDF]

Cell Communication and Signaling
Background Hematopoietic stem cells (HSCs) maintain blood production via tightly regulated differentiation. Disruptions at this level can lead to myelodysplastic syndromes (MDS), characterized by ineffective hematopoiesis and marrow failure.
Xiaoling Shi, Yushi Liu, Lejun Huang, Yuxin Ou, Xinyu Chen, Yiming Ling, Yiyue Zhang, Qing Lin   +7 more
doaj   +2 more sources

Using a Natural Clay Mineral as an Active Drug Carrier to Promote Hair Growth [PDF]

Pharmaceuticals
Background: Topical minoxidil remains the only FDA-approved treatment for hair loss, yet its clinical efficacy is compromised by organic-solvent-induced scalp irritation and poor patient adherence. This study aimed to evaluate natural illite as a carrier
Zhiqing Liu, Wenhua Huang, Shanhua Xu, Meilan Nan, Xian Cui, Yue Wang, Zhehu Jin, Wan Meng, Jingbi Meng, Longquan Pi   +9 more
doaj   +2 more sources

The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil

Pharmaceutics, 2022
The purpose of this study was to evaluate mechanisms behind the intestinal permeability of minoxidil, with special emphasis on paracellular transport, and elucidate the suitability of minoxidil to be a reference drug for Biopharmaceutics Classification ...
Milica Markovic, Moran Zur, Sapir Garsiani, Daniel Porat, Sandra Cvijić, Gordon L. Amidon, Arik Dahan   +6 more
doaj   +2 more sources

Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

Pharmaceutics, 2018
In this work, we examined enhanced skin delivery of minoxidil applied in nanoemulsions incorporating skin penetration enhancers. Aliquots of fully characterized oil-in-water nanoemulsions (1 mL), containing minoxidil (2%) and the skin penetration ...
, Jeffrey E Grice, Michael S Roberts
exaly   +3 more sources

Relative efficacy of minoxidil in combination with other treatments for androgenic alopecia: a network meta-analysis based on randomized controlled trials [PDF]

Frontiers in Medicine
BackgroundAndrogenetic alopecia is the most prevalent form of progressive hair loss. Minoxidil is widely regarded as a standard treatment for this condition.
Yinfeng Xia, Hong Chen, Yongsong Chen, Zhiyong Chen   +3 more
doaj   +2 more sources

Phototherapy with Topical Minoxidil in Vitiligo: A Randomized Control Trial [PDF]

Indian Dermatology Online Journal
Background: Phototherapy is the most commonly used treatment for vitiligo, with initial pigment appearing at the perifollicular site, eventually coalescing into uniform pigmentation due to melanocyte migration from hair follicles.
Sejal Bajoria, Chakravarthi R. Srinivas, Nithya Satish, Riya Sukhija, Kriti Jain, Garima Manocha, Laxman Besra   +6 more
doaj   +2 more sources

Xerostomia as a Rare Adverse Effect of Low‐Dose Oral Minoxidil: A Case Report With Recurrence After Rechallenge [PDF]

Clinical Case Reports
Low‐dose oral minoxidil (LDOM) is an emerging option for the treatment of female pattern hair loss (FPHL), generally well tolerated at doses under 1 mg/day.
Nicolò Rivetti
doaj   +2 more sources

Acne Scar Management: Minoxidil as a Promising Approach or a Mirage? [PDF]

International Journal of Biomedicine, 2023
Atrophic and hypertrophic scars can result from various conditions, such as acne, trauma, and surgery. Minoxidil, a medication used for the treatment of severe hypertension and hair loss, has been explored as a potential treatment for scars.
Ramadan S. Hussein, Salman Bin Dayel
doaj   +1 more source

Simultaneous determination of minoxidil and minoxidil sulfate by high-performance liquid chromatography with UV-detection and its applications

Medicine in Drug Discovery, 2020
Aims: Minoxidil is a hair growth drug for treating androgenetic alopecia. Although minoxidil is generally administered as a topical formulation, this prodrug must be converted to its active form (minoxidil sulfate) by sulfotransferase in hair follicle ...
Mio Ichida, Chiharu Fujita, Rena Sumie, Ryotaro Miyano, Hajime Inoue   +4 more
doaj   +1 more source