Results 181 to 190 of about 7,334 (206)
Some of the next articles are maybe not open access.
MINOXIDIL IN RESISTANT HYPERTENSION
The Lancet, 1977Minoxidil in combination with propranolol and diuretics controlled the blood-pressure in a group of hypertensive patients who were resistant to treatment with large doses of standard drugs. The main problem was fluid retention but subjective side-effects were fewer than in a comparable group on other drugs.
H.J. Dargie, Colin T. Dollery, J. Daniel
openaire +5 more sources
Pharmacokinetic studies of minoxidil
Clinical Pharmacology & Therapeutics, 1972The disposition of minoxidil, a new direct arterial vasodilator and potent antihypertensive, was studied in 7 hypertensive patients. Following oral administration of 14C‐labeled minoxidil, there was a rapid removal of the drug with a plasma half‐life of 4.2 hours.
Richard C. Thomas +2 more
openaire +3 more sources
Chest, 1993
A 52-year-old man ingested 60 ml of 2 percent topical minoxidil solution resulting in severe hypotension and tachycardia. He was resuscitated with intravenously administered crystalloid solution and treated with intravenously administered dopamine, resulting in a partial hemodynamic improvement.
Andrew Macmillan +2 more
openaire +3 more sources
A 52-year-old man ingested 60 ml of 2 percent topical minoxidil solution resulting in severe hypotension and tachycardia. He was resuscitated with intravenously administered crystalloid solution and treated with intravenously administered dopamine, resulting in a partial hemodynamic improvement.
Andrew Macmillan +2 more
openaire +3 more sources
Minoxidil in refractory hypertension
The Journal of Pediatrics, 1975A life-threatening, severe, hypertension refractory to conventional antihypertensive drugs developed in a 10-year-old girl in association with a functional renal transplant. Minoxidil, a new vasodilator, proved to be a life-saving antihypertensive drug and prevented the removal of the functional transplant.
openaire +3 more sources
Telogen effluvium and minoxidil
Journal of the American Academy of Dermatology, 1989We have seen two patients with telogen effluvium during treatment with topical minoxidil for common ...
Alfredo Rebora, A. Bardelli
openaire +3 more sources
The history of the development of minoxidil
Clinics in Dermatology, 1988Abstract By means of increasingly more penetrating research efforts, the pharmaceutical industry is acquiring ever greater insight into disease and other adverse processes. This results in the discovery and development of drugs with more highly complex actions.
openaire +3 more sources
Pharmacology and Pharmacokinetics of Minoxidil
Journal of Cardiovascular Pharmacology, 1980Minoxidil is a potent oral vasodilator acting on the arteriolar side of the circulation. Reflex tachycardia and sodium retention are consequences of increased sympathetic activity. Its biotransformation is 90% hepatic, with no evidence of accumulation of minoxidil when it is given chronically in patients with either normal renal function. The half-life
Melton B. Affrime, David T. Lowenthal
openaire +3 more sources
Minoxidil and Wound Contraction
Annals of Plastic Surgery, 1997Minoxidil has been proposed as a potential topical inhibitor of wound contraction and proliferative scarring. Suggestions for this application are derived from in vitro investigations demonstrating inhibition of various fibroblastic functions. The purpose of this study was to attempt to establish in vivo support of these effects using an established ...
Martin C. Robson +5 more
openaire +2 more sources
Fluid Retention with Minoxidil
Annals of Internal Medicine, 1978Excerpt To the editor: In their discussion of resistant hypertension in a recent issue (1), Drs.
M. J. Reichgott, C. V.S. Ram
openaire +3 more sources
Minoxidil and Cardiac Enlargement
JAMA: The Journal of the American Medical Association, 1978To the Editor.— The article on longterm use of minoxidil by Mitchell and Pettinger (239:2131, 1978) describes nine of 17 current patients with an increase in heart size. Four might have been due to poor blood pressure (BP) control (and presumed progressive left ventricular enlargement), but in five there was no good explanation.
openaire +3 more sources