Results 51 to 60 of about 7,292 (203)

Minoxidil Sulfate Is the Active Metabolite that Stimulates Hair Follicles

, 1990
An important step in understanding minoxidil's mechanism of action on hair follicles was to determine the drug's active form. We used organ-cultured vibrissa follicles to test whether it is minoxidil or its sulfated metabolite, minoxidil sulfate, that ...
Johnson, Garland A, Buhl, Allen E, Waldon, Daniel J, Baker, Carolyn A   +3 more
core   +1 more source

Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights

International Journal of Dermatology, EarlyView.
Summary of the microbiome‐lipid‐microinflammation axis in androgenetic alopecia (AGA). Altered sebaceous gland activity, shifts in microbial abundance on the scalp and hair follicle, and follicular microinflammation interact bidirectionally, each reinforcing the others.
Aditya K. Gupta, Elizabeth M. Teasell, Amanda Liddy, Vasiliki Economopoulos   +3 more
wiley   +1 more source

Comparative efficacy of topical minoxidil alone against combination of topical minoxidil and platelet rich plasma in women with female pattern hair loss—A pilot, open randomised trial

Indian Journal of Dermatology, 2023
Background: Female pattern hair loss (FPHL) affects a significant proportion of population and poses a major therapeutic challenge. Aims and Objectives: To compare the efficacy and safety profile of combination of topical minoxidil 2% plus platelet rich ...
Akanksha Agarwal, Vibhu Mendiratta
doaj   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

International Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo, Isotta Giunipero di Corteranzo, Pietro Quaglino, Simone Ribero, Francois Rosset   +4 more
wiley   +1 more source

Topical minoxidil reported hair discoloration: a cross-sectional study

Dermatology Reports, 2023
Minoxidil is a widely utilized medication for various hair conditions, such as androgenic alopecia. The current literature lacks an original study that reports the possibility of this medication causing a well-noticed side effect, hair discoloration ...
Ghada Alhayaza, Alanoud Hakami, Lenah H. AlMarzouk, Abddullah A. Al Qurashi, Ghada Alghamdi, Ruaa Alharithy   +5 more
doaj   +1 more source

Minoxidil: Inhibition of Proliferation of Keratinocytes In Vitro

, 1991
Previous studies have suggested that minoxidil stimulates growth of keratinocytes, possibly in a manner similar to the action of epidermal growth factor.
O'Keefe, Edward, Payne, Richard
core   +1 more source

How to optimise tournament draws: The case of the FIFA World Cup

International Transactions in Operational Research, EarlyView.
Abstract The organisers of major sports competitions use different policies with respect to constraints in the group draw. Our paper aims to rationalise these choices by analysing the trade‐off between attractiveness (the number of games played by teams from the same geographic zone) and fairness (the departure of the draw mechanism from a uniform ...
László Csató
wiley   +1 more source

Microneedle‐Assisted Delivery of PEGylated Recombinant Human Fusion Collagen for Androgenetic Alopecia: Preclinical and Pilot Clinical Evidence [PDF]

J Cosmet Dermatol
ABSTRACT Background Androgenetic alopecia (AGA), the most common form of progressive hair loss in men, significantly impairs both physical and psychological well‐being. While traditional research has predominantly focused on cellular components and signaling pathways, the extracellular matrix (ECM)—particularly collagen—is increasingly recognized as ...
Jin M, Kong Y, Ge L, Luo Y, Li C, Meng J, Jin Z, Pi L.   +7 more
europepmc   +2 more sources

Minoxidil-induced cardiac hypertrophy in guinea pigs

, 1999
To investigate whether during cardiac hyper trophy changes occur in contractile protein composition and in mechanical and energetic properties of the myocardium, contractile protein composition, isometric force and adenosine triphosphate (ATP ...
Borgdorff, P., Van Der Velden, J., Stienen, G. J M   +2 more
core   +1 more source

Association of Nasal and Inhalant Corticosteroids With Pediatric Perioral Dermatitis: A TriNetX Retrospective Cohort Study

Pediatric Dermatology, EarlyView.
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle, Caitlyn Curley, Dylan Wambold, Basira Iginla, Erum N. Ilyas   +4 more
wiley   +1 more source