Results 71 to 80 of about 1,772,811 (262)
Fully Open-Source Meeting Minutes Generation Tool
With the increasing use of online meetings, there is a growing need for efficient tools that can automatically generate meeting minutes from recorded sessions.
Amma Liesvarastranta Haz +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Croquer le travail : une commande du CEA
This article revisits the key theme of the journal ITTI, namely the relationship between the work of images and the images of work. The questions: who paints what work, where and how are again developed here by showing the singular interaction between a ...
Michèle Dupré
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Design of a fast cassette autoclaves for medical devices
Ensuring patient safety in healthcare necessitates the sterilization of medical devices. However, traditional autoclaves are impractical for certain medical settings due to their size, bulkiness, and time-consuming nature.
Le Hoai Nam +6 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Deflection Encounters: Motivational Interviewing and Maximal Minutes
EN | Abstract: This article is a practice review for the application of Motivational Interviewing (MI) to be applied to First Responder Deflection programming.
Michael D. Clark
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source

