Results 91 to 100 of about 4,291 (262)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Tarbiyah in the Digital Age: An Islamic Behavioral Framework for Reducing the Duration of Gadget Use in Preschoolers

International Journal of Islamic Thought and Humanities
This study addresses the growing issue of excessive gadget use by framing behavior modification within the principles of Islamic child-rearing (Tarbiyah al-Awlad).
Husni Abdillah, Ratna Pangastuti, Nasrul Fuad Erfansyah   +2 more
doaj   +1 more source

Responsibilities of Notaryas Class II Auction Officer Regarding the Deed of Auction Minute He Makes

Golden Ratio of Data in Summary
Auction is a method of selling goods or services conducted through an open bidding process, which is strictly regulated in Indonesia by laws and regulations, including the Minister of Finance Regulation No. 27/PMK.06/2016. In implementing auctions, the auction minutes act is important as an authentic document that records the auction process and its ...
Nabila Djuliana Suria Subrata Subrata, Ainul Mardiyah Salsabila, Ummi Maskanah   +2 more
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Urgency of Legal Regulation On Investigator Authorization To Seize And Obtain Original Notarial Deeds

Yurisdiksi: Jurnal Wacana Hukum dan Sains
This study examines the urgency of regulating and harmonizing the authority for the seizure and confiscation of notarial minutes in the Indonesian legal system.
Fauza Shofia, Herlindah, M. Sudirman
doaj   +1 more source

The Validity of Giving Barcode to Maintain Security In Notary Deed Minutes [PDF]

. Cyber notaryis the role of Notaries in the development of functions by using electronic transactions. The objectives of this study: 1) To find out and examine the legal consequences of using barcodes for Notary deeds in order to improve security ...
Hafidz, Jawade, Vanjeka, Restu Naufal
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Werda Notary's Responsibility for the Loss of Minutes of the Deed He Made [PDF]

This study aims to analyze: 1) The legal responsibility of notaries for the loss of minutes of deeds they have made. 2) Legal protection of notaries related to the deeds they have made.
Utami, Siska Nur
core