Results 121 to 130 of about 4,291 (262)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Analysis of the Role and Responsibilities of Notaries in Storing Minutes of Deeds [PDF]
Notaries have an obligation to store and maintain the minutes of the deeds they make, explained in Article 16 paragraph (1) letter b UUJN which states that Notaries have an obligation to make deeds in the form of minutes and also store them as Notary ...
Febriani, Nisrina
core
God, Grief and Community:Commemoration of the Great War in Huddersfield, c. 1914-1929 [PDF]
, 2009 This thesis is concerned with the borough of Huddersfield, in the West Riding of Yorkshire, during and after the First World War. It examines the creation of war memorials at all levels, from the borough-wide official scheme, through those relating to ...
Brook, Anne Christine
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Smithfield Presbyterian Church minutes, August 1913
, 1913 Smithfield Presbyterian Church minutes about the warranty deed signed by G.W.
core
The Binding Force Of A Deed Not Read By A Notary
This study aims to examine the validity of notarial deeds that are not read out in the presence of the parties and witnesses, as well as to analyze and determine the role of the Notary Supervisory Council in terms of enforcement under the laws of the ...
Mariane, Irene
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Reforming of Related Instruments for Indonesia's Cyber Notary Concept Implementation
Jurnal Ilmu KenotariatanThe concept of a cyber notary or electronic notary, represents a significant shift in the progression of conventional notaries to more modern ones. However, Indonesia lacks regulation synchronization, making the concept difficult to apply. Therefore, the
Dilla Naharul Mumtazh +1 more
doaj
Reduction of thoraco-lumbar kyphosis results in the alleviation of low back pain in an adolescent basketball player: a Chiropractic Biophysics® (CBP®) case report. [PDF]
J Phys Ther Sci, 2023 Oakley PA, Haas JW, Harrison DE.
europepmc +1 more source