Results 81 to 90 of about 79,041 (350)
Advanced Science, EarlyView.Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang +12 more
wiley +1 more source
Resources, 2013 The Wuppertal Institute developed, in the early 1990s, an input-oriented lifecycle-wide resource accounting method, the “Material Input per Service-Unit” concept (MIPS), today also referred to as “Material Footprint”.
Mathieu Saurat, Michael Ritthoff
doaj +1 more source
MIPS: The good, the bad and the useful [PDF]
Many authors are critical of the use of MIPS (Millions of Instructions per Second) as a measure of computer power. Some feel that MIPS are meaningless. While there is justification for some of the criticism of MIPS, sometimes the criticism is carried too
Richardson, Jerry K.
core +1 more source
Spitzer Space Telescope Observations of Low Mass X-ray Binaries [PDF]
, 2008 We present preliminary results from our archival Spitzer Space Telescope program aimed at characterizing the mid-IR properties of compact objects, both isolated and in binary systems, i.e.
Christopher R. Gelino +4 more
core +2 more sources
Advanced Science, EarlyView.Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
Going the distance for protein function prediction: a new distance metric for protein interaction networks [PDF]
, 2013 Due to an error introduced in the production process, the x-axes in the first panels of Figure 1 and Figure 7 are not formatted correctly. The correct Figure 1 can be viewed here: http://dx.doi.org/10.1371/annotation/343bf260-f6ff-48a2-93b2 ...
Cao, Mengfei +6 more
core +4 more sources
Advanced Science, EarlyView.This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab +8 more
wiley +1 more source
Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement
Advanced Science, EarlyView.The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang +7 more
wiley +1 more source
Journal of Analytical Methods in Chemistry, 2019 Ferulic acid (FA), an important phenolic acid, is widely distributed in higher plants and presents many pharmacological effects. Therefore, sensitive determination of FA in complex matrix is necessary.
Zhihong Wang +4 more
doaj +1 more source
Detection of Non-Melanoma Skin Cancer by in vivo Fluorescence Imaging with Fluorocoxib A
Neoplasia: An International Journal for Oncology Research, 2015 Non-melanoma skin cancer (NMSC) is the most common form of cancer in the US and its incidence is increasing. The current standard of care is visual inspection by physicians and/or dermatologists, followed by skin biopsy and pathologic confirmation.
Hyejun Ra +8 more
doaj +1 more source