2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression
The MID1 ubiquitin ligase activates mTOR signaling and regulates mRNA translation. Misregulation of MID1 expression is associated with various diseases including midline malformation syndromes, cancer and neurodegenerative diseases. While this indicates that MID1 expression must be tightly regulated to prevent disease states specific mechanisms ...
Kristoffer Unterbruner +6 more
openaire +6 more sources
Habitat selection of moose in Sweden in managed boreal forests with Pinus contorta and P. sylvestris
Human land use can take advantage of using exotic species to increase financial benefits. However, the use of exotic tree species might affect ecosystem functioning, potentially including the habitat use and movement behaviour of animals, modifying their ecological impact, and interactions with human land use.
Maria Bodlund +5 more
wiley +1 more source
POS0191 THE VALUE OF MIR-20B, MIR-22, MIR-26A, MIR-125B AND MIR-221 IN RHEUMATOID ARTHRITIS [PDF]
M. Ciesla +3 more
openaire +1 more source
Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke
MicroRNAs (miRNAs or miRs) are small (19-23 nt) non-coding RNA molecules that are endogenous regulators of gene expression. Previous studies have found that some miRNAs are related to the progression of ischemia in the cerebral artery. Furthermore, a recent study found a significant association between miRNA single nucleotide polymorphisms (SNPs) and ...
Gun Ho, Choi +9 more
openaire +3 more sources
Fragmented and Dealigned: The 2024 British General Election and the Rise of Place‐Based Politics
Abstract While the outcome of the 2024 British general election signalled a resounding repudiation of the incumbent government—returning a 231‐seat swing from the Conservatives to Labour—it did not radically overturn the geography of electoral outcomes in England and Wales.
Will Jennings +3 more
wiley +1 more source
Inchoativity and mirativity in Italo-Romance and Balkan Slavic verbal periphrases.
This paper investigates the properties of GO and TAKE used as functional verbs to express the beginning of an action or a state (inchoativity) or a sense of surprise, wonder, astonishment, or regret (mirativity) as found in a group of multiple verb ...
Vincenzo Nicolò Di Caro, Luca Molinari
doaj +1 more source
Exploring the Impact of miR-10a, miR-141, miR-200a and miR-3658 on Cystinuria
Introduction: Cystinuria is an inherited disorder characterized by impaired proximal tubular reabsorption of cystine, resulting in recurrent cystine stone formation. Mutations in the SLC3A1 and SLC7A9 genes are the main genetic causes of the disease, while variants in PBX1 have also been associated with cystinuria in specific populations.
Daniel Cernach Ayres +14 more
openaire +1 more source
Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC [PDF]
The performance of circulating biomarkers for the diagnosis of hepatocellular carcinoma (HCC) is sub-optimal. In this study we tested circulating microRNAs as biomarkers for HCC in cirrhotic patients by performing a two stage study: a discovery phase conducted by microarray and a validation phase performed by qRT-PCR in an independent series of 118 ...
FORNARI, FRANCESCA +14 more
openaire +5 more sources
Fronting in Old Catalan: Asymmetries between Narration and Reported Speech1
Abstract This article explores the distribution, syntax, and information structure of XVS clauses in the narrative text and the reported speech of a thirteenth‐century Old Catalan chronicle, the Llibre dels Fets. It is shown that XVS occurs mainly within reported speech and in embedded clauses.
Afra Pujol i Campeny
wiley +1 more source

