Results 311 to 320 of about 447,640 (362)

Lactate as a metabolic–epigenetic signal linking high-intensity interval training (HIIT) to miRNA-Centered remodeling of the skeletal muscle methylome and transcriptome

Lei Zhou, Soroosh Mozaffaritabar, Kumpei Tanisawa, Takuji Kawamura, Mitsuru Higuchi, István Boldogh, Xueqing Ba, Sataro Goto, George A. Brooks, Yaodong Gu, Zsolt Radák   +10 more
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MicroRNAs Modulating Cancer Immunotherapy Mechanisms and Therapeutic Synergies. [PDF]

Cancers (Basel)
Mangang NL, Gargasz SK, Murugan SG, Kumar M, Shukla GC, Vijayaraghavalu S.   +5 more
europepmc   +1 more source

The clinical significance of circulating microRNAs as biomarkers in lung cancer diagnosis and prognosis. [PDF]

Discov Oncol
Fan J, Shen D, He L, Yan C, Li H, Zhang Y, Bai X.   +6 more
europepmc   +1 more source

miRNAs and cancer.

Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research, 2006
openaire   +2 more sources

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Endogenous miRNA Sponges.

Methods in molecular biology, 2021
MicroRNAs (miRNAs) are a class of noncoding RNAs of 17-22 nucleotides in length with a critical function in posttranscriptional gene regulation. These master regulators are themselves subject to regulation both transcriptionally and posttranscriptionally.
Ayşe Hale Alkan, B. Akgül
semanticscholar   +3 more sources

Expression of miRNA-155, miRNA-223, miRNA-31, miRNA-21, miRNA-125b, and miRNA-146a in the Inflammatory Pathway of Hidradenitis Suppurativa

Inflammation, 2016
Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. We evaluated the messenger RNA (mRNA) expression levels of six selected inflammation-related miRNAs in lesional and ...
S. Hessam, M. Sand, M. Skrygan, T. Gambichler, F. G. Bechara   +4 more
openaire   +2 more sources

miRNA–miRNA crosstalk: from genomics to phenomics

Briefings in Bioinformatics, 2016
The discovery of microRNA (miRNA)-miRNA crosstalk has greatly improved our understanding of complex gene regulatory networks in normal and disease-specific physiological conditions. Numerous approaches have been proposed for modeling miRNA-miRNA networks based on genomic sequences, miRNA-mRNA regulation, functional information and phenomics alone, or ...
Juan, Xu, Tingting, Shao, Na, Ding, Yongsheng, Li, Xia, Li   +4 more
openaire   +2 more sources

Viral miRNAs

2011
Since 2004, more than 200 microRNAs (miRNAs) have been discovered in double-stranded DNA viruses, mainly herpesviruses and polyomaviruses (Nucleic Acids Res 32:D109-D111, 2004). miRNAs are short 22  ±  3 nt RNA molecules that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTR) of target mRNAs, thereby inducing ...
Karlie, Plaisance-Bonstaff, Rolf, Renne
openaire   +2 more sources

MiRNA Editing

2010
RNA editing by A-to-I modification is a widespread mechanism in complex organisms that leads to the posttranscriptional alteration of protein coding as well as noncoding sequences. MiRNA transcripts have been recognized as a major target for RNA editing enzymes, and single-nucleotide changes through editing can impact the biogenesis of mature miRNAs ...
Dylan E, Dupuis, Stefan, Maas
openaire   +2 more sources