Incidental Detection of Situs Inversus Totalis Following Identification of an Unexpected Left-Sided Brachiocephalic Trunk on Carotid Duplex Ultrasound: A Case Report. [PDF]
CureusNabhan E +4 more
europepmc +1 more source
Advanced Science, EarlyView.This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao +5 more
wiley +1 more source
Reply to Zhabagin and Sabitov: Novel knowledge is gained through fresh data and new analytical methods, not through paraphrasing. [PDF]
Proc Natl Acad Sci U S AAskapuli A.
europepmc +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Right-sided aortic arch with anomalous coronary artery origin and concomitant Stanford type A dissection: A rare case report. [PDF]
Radiol Case RepD'Arma GMA +5 more
europepmc +1 more source
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Physiology and BiophysicsThe Image of Research 2011FinalistMy research investigates the estrogen receptor-? (ER???signaling mechanisms that regulate prostate gland development and growth. ER?
Calderon, Esther
core
A Review of Failure Modes and Safety Strategies of Lithium‐Ion Batteries from Materials to Systems
Advanced Science, EarlyView.A cascade‐aware framework is presented for lithium‐ion battery safety, linking thermal runaway initiation, acceleration, runaway reaction, and propagation with material‐, cell/pack‐, and system‐level interventions. By integrating failure mechanisms, quantitative safety indicators, and staged interception strategies, this review highlights how safer ...
Jin Hyeok Yang +8 more
wiley +1 more source
Longitudinal in vivo OCT/OCTA of gastric tumor microvasculature via an implantable optical window. [PDF]
Biomed Opt ExpressDu F +7 more
europepmc +1 more source
Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond
Advanced Science, EarlyView.Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu +5 more
wiley +1 more source