Results 81 to 90 of about 17,812,796 (266)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Brain–computer interface game applications for combined neurofeedback and biofeedback treatment for children on the autism spectrum [PDF]

, 2014
Individuals with autism spectrum disorder (ASD) show deficits in social and communicative skills, including imitation, empathy, and shared attention, as well as restricted interests and repetitive patterns of behaviors.
Lim, Theodore; id_orcid, Sandy Louchart, Theodore Lim, Pineda, Jaime A, Neil Suttie, Elisabeth V. C. Friedrich, Jaime A. Pineda, Aparajithan Sivanathan, Friedrich, Elisabeth V. C., Louchart, Sandy, Friedrich, Elisabeth VC, Suttie, Neil, Louchart, Sandy Jean-Jacques, Sivanathan, Aparajithan, Pineda, Jaime A., Lim, Theodore   +15 more
core   +1 more source

A Historical Approach to the Mirror Neuron System

Iatreia
Introduction: Three decades after the discovery of mirror neurons (MN), interest in understanding their function as a system persists, and their impact on neuroscience, biology, medicine, and psychology continues to consolidate.
Palacios-Sánchez, Leonardo, Botía, Inés, Palacios-Espinosa, Ximena   +2 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

On computational models of theory of mind and the imitative reinforcement learning in spiking neural networks

Scientific Reports
Theory of Mind is referred to the ability of inferring other’s mental states, and it plays a crucial role in social cognition and learning. Biological evidences indicate that complex circuits are involved in this ability, including the mirror neuron ...
Ashena Gorgan Mohammadi, Mohammad Ganjtabesh   +1 more
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

The mirror neuron system: New frontiers

, 2008
Since the discovery of mirror neurons, much effort has been invested into Studying their location and properties in the human brain. Here we review these original findings and introduce the Main topics of this special issue of Social Neuroscience.
Christian Keysers, Keysers C, Keysers, Christian, Fadiga, Luciano, Luciano Fadiga   +4 more
core   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Anatomy and Physiology of the Mirror Neuron System

, 2015
In this article, we treat the mirror neuron system defined as a set of brain regions active both when an individual performs an action and when he or she perceives another individual performing a similar action.
R. Viaro, L. Fadiga, B. Tia
core   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source