Results 161 to 170 of about 96,419 (357)

SPIN (Scottish Pregnancy Intervention) study: a multicenter, randomized controlled trial of low-molecular-weight heparin and low-dose aspirin in women with recurrent miscarriage [PDF]

, 2010
Peter Clark, Isobel D. Walker, Peter Langhorne, Lena Crichton, Andrew Thomson, M. Greaves, Sonia Whyte, Ian A. Greer   +7 more
openalex   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Chorionic biopsy and miscarriage in first trimester

, 1984
letterhttp://dx.doi.org/10.1016/S0140-6736(84)90955-
Gustavii, Bjorn
core  

Does access to health insurance reduce the risk of miscarriages? Evidence from Mexico’s Seguro popular [PDF]

, 2015
Tobias Pfütze
openalex   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Women's Experiences of Miscarriage

, 2011
Full text is available to authenticated members of The University of Auckland only.In New Zealand, it is estimated that around 20% of pregnancies end in miscarriage. Recurrent miscarriage is thought to affect 1% of women.
Barnes, Sylvia
core  

SELECTED ORAL COMMUNICATION SESSION, SESSION 05: RECURRENT MISCARRIAGE, Monday 4 July 2011 10:00 - 11:30 [PDF]

, 2011
Marie Lund, Mads Kamper‐Jørgensen, Henriette Svarre Nielsen, Øjvind Lidegaard, Anne‐Marie Nybo Andersen, O.B. Christiansen, S. P. Kaandorp, T. van Mens, Joris van der Post, Barbara A. Hutten, Harry R. Büller, Fulco van der Veen, Saskia Middeldorp, Mariëtte Goddijn, Ole Bjarne Christiansen, Emma Larsen, Henriette Svarre Nielsen, Philippe Merviel, Rosalie Cabry, R. Temstet, B. Delaby, E. Lourdel, C. Penrose St. Amant, María Paz Muñoz, Francisco Raga, Peter L. Ferrer, Carmen Ródenas Calatayud, Manuela Expósito Ruíz, Subir Kumar Bhattacharya, Alison Lowit, Edwin Amalraj Raja, Tahir Mahmood, A. J. Lee, Anne Templeton, Subir Kumar Bhattacharya   +34 more
openalex   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source