Results 141 to 150 of about 69,062 (306)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Acute stroke imaging research roadmap [PDF]

, 2008
Albers, G.W., Alexandrov, A.V., Alger, J.R., Bammer, R., Baron, J.-C., Davis, S., Demaerschalk, B.M., Derdeyn, C.P., Donnan, G.A., Eastwood, J.D., Fiebach, J.B., Fisher, M., Furie, K.L., Goldmakher, G.V., Hacke, W., Kidwell, C.S., Kloska, S.P., Kohrmann, M., Koroshetz, W., Lee, T.Y., Lees, K.R., Wintermark, M.   +21 more
core   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Unlocking the Potential of Thermal Post-Treatments: A Study on Odor Emission Control in <i>Eucalyptus</i> Wood Particleboard. [PDF]

Molecules
Yin W, Zhang Y, Li C, Wu B, Yang Z, Huang H, Luo B, Du G, Zhao P, Yang X.   +9 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

3D-Printed Devices in Interventional Radiotherapy (Brachytherapy) Applications: A Literature Review. [PDF]

J Pers Med
Rosa E, Raponi S, Fionda B, Vaccaro M, Lancellotta V, Napolitano A, Ciasca G, Bannoni L, Cornacchione P, Tagliaferri L, De Spirito M, Placidi E.   +11 more
europepmc   +1 more source

IMPROVING COST/BENEFIT ANALYSIS FOR HACCP AND MICROBIAL FOOD SAFETY: AN ECONOMIST'S OVERVIEW [PDF]

HACCP, cost/benefit analysis, Food Consumption/Nutrition/Food Safety,
Roberts, Tanya, Unnevehr, Laurian J.
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Emerging Trends in the Application of Nanosuspension-Based Biomaterials for Anticancer Drug Delivery. [PDF]

Int J Nanomedicine
Aldeeb MME, Wilar G, Suhandi C, Mohammed AFA, Mahmoud SA, Elamin KM, Wathoni N.   +6 more
europepmc   +1 more source

Scope, Strategy and Structure: The Dynamics of Knowledge Networks in Medicine [PDF]

The objective of this paper is to analyse the dynamics of networks in which new knowledge emerges and through which it is exchanged. Our conjecture is that the structure of a network cannot be divorced from the dynamics of the knowledge underpinning its ...
Consoli, Davide, Ramlogan, Ronnie
core   +1 more source